Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | CES1 | P23141 | 4/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1036903 | 1.00 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL17839027 | 1.00 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL7611733 | 1.00 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL1032903 | 1.00 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL1032589 | 1.00 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL7929478 | 1.00 | DNM1 (0.64) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL31730241 | 0.98 | DNM1 (0.68) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL5673150 | 0.98 | DNM1 (0.68) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL11044320 | 0.98 | DNM1 (0.68) | DNM1CA2CA1CES2CES1 | |
| Acetic Acid SCHEMBL1037570 | 0.98 | DNM1 (0.59) | DNM1CA2CA1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112752786-B | Polycarbonate compositions with improved oxidative stability and methods for preparing same | SABIC环球技术有限责任公司 | 2023-06-09 | — | — | CN | claimed |
| US-7122613-B1 | Method for the production of polycarbonates | GENERAL ELECTRIC COMPANY (US) | 2006-10-17 | — | — | US | claimed |
| EP-1578840-A1 | METHOD FOR THE PRODUCTION OF POLYCARBONATES | General Electric Company (US) | 2005-09-28 | — | — | EP | claimed |
| WO-2004060963-A1 | METHOD FOR THE PRODUCTION OF POLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 2004-07-22 | — | — | WO | claimed |
| EP-0883594-B1 | PROCESS FOR THE PRODUCTION OF 1,2-DIACETOXY ESTERS | EASTMAN CHEM CO (US) | 2001-09-05 | — | — | EP | claimed |
| EP-0883594-A1 | PROCESS FOR THE PRODUCTION OF 1,2-DIACETOXY ESTERS | EASTMAN CHEMICAL COMPANY (US) | 1998-12-16 | — | — | EP | claimed |
| EP-0783475-B1 | PROCESS FOR PREPARING 1,3-ALKANEDIOLS AND 3-HYDROXYALDEHYDES | SHELL INT RESEARCH (NL) | 1998-12-09 | — | — | EP | claimed |
| WO-1997031885-A1 | PROCESS FOR THE PRODUCTION OF 1,2-DIACETOXY ESTERS | EASTMAN CHEMICAL COMPANY (US) | 1997-09-04 | — | — | WO | claimed |
| US-5663422-A | FROM EPOXIDE AND ACETIC ANHYDRIDE, PHOSPHONIUM ACETATE CATALYST | EASTMAN CHEMICAL COMPANY (US) | 1997-09-02 | — | — | US | claimed |
| EP-0783475-A1 | PROCESS FOR PREPARING 1,3-ALKANEDIOLS AND 3-HYDROXYALDEHYDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-07-16 | — | — | EP | claimed |
| WO-1996010550-A1 | PROCESS FOR PREPARING 1,3-ALKANEDIOLS AND 3-HYDROXYALDEHYDES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1996-04-11 | — | — | WO | claimed |
| US-20250340697-A1 | METHOD FOR THE MANUFACTURE OF POLYCARBONATE | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2025-11-06 | — | — | US | disclosed |
| EP-4532597-A1 | METHOD FOR THE MANUFACTURE OF POLYCARBONATE | SABIC Global Technologies B.V. (NL) | 2025-04-09 | — | — | EP | disclosed |
| CN-119317662-A | Method for producing polycarbonate | SABIC环球技术有限责任公司 | 2025-01-14 | — | — | CN | disclosed |
| US-12084542-B2 | Polycarbonate compositions with improved oxidation stability and methods of manufacturing the same | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2024-09-10 | — | — | US | disclosed |
| US-5463145-A | Reacting ethylene oxide, carbon monoxide, hydrogen in organic solvent in presence of non-phosphine-ligated cobalt catalyst and lipophilic quaternary phosphonium salt promoter, extracting 3-hydroxypropanal with water, hydrogenating | SHELL OIL COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| US-5459226-A | Melt extrusion in presence of tetraorganophosphonium carboxylate salt | GENERAL ELECTRIC COMPANY (US) | 1995-10-17 | — | — | US | disclosed |
| EP-0671428-A1 | Method for making polycarbonates | GENERAL ELECTRIC COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5412061-A | Polycarbonate melt condensation synthesis using a tetraorganophosphonium carboxylate salt catalyst | GENERAL ELECTRIC COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| US-4518715-A | Process for producing ethylene glycol using a ruthenium-copper catalyst | TEXACO INC. (US) | 1985-05-21 | — | — | US | disclosed |