SCHEMBL11044338

SCHEMBL11044338

C[Si](CCP(c1ccccc1)c1ccccc1)(CCP(c1ccccc1)c1ccccc1)CCP(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10709552 0.86 CYP3A4 (0.36) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL10728260 0.86 CYP3A4 (0.36) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL10727558 0.84 CYP3A4 (0.35) CYP3A4TDP1ESR1ESR2
SCHEMBL15842556 0.84
SCHEMBL10384104 0.83 CYP3A4 (0.33) CYP3A4TDP1
SCHEMBL12908269 0.82 CYP3A4 (0.34) CYP3A4TDP1
SCHEMBL11044528 0.81 CYP3A4 (0.39) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL10732697 0.80 CYP3A4 (0.35) CYP3A4TDP1ESR1ESR2
Carbon Monoxide SCHEMBL11047916 0.79 CYP3A4 (0.31) CYP3A4TDP1
Carbon Monoxide SCHEMBL10787646 0.79 CYP3A4 (0.31) CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109331878-B Catalyst for ethylene oligomerization 天津科技大学 2021-08-13 CN claimed
CN-109331878-B Catalyst for ethylene oligomerization 天津科技大学 2021-08-13 CN disclosed
US-4480137-A ALDEHYDES FROM ALPHA-OLEFINS; HEAT RESISTANCE; CATALYST SELECTIVITY EXXON RESEARCH & ENGINEERING COMPANY (US) 1984-10-30 US disclosed
US-4454353-A Trihydrocarbyl silyl substituted alkyl diaryl phosphine transition metal complexes and their use as homogeneous hydroformylation-aldolization catalysts EXXON RESEARCH AND ENGINEERING CO. (US) 1984-06-12 US disclosed
US-4451673-A REACTING OLEFINS WITH CARBON MONOXIDE AND HYDROGEN TO YIELD ALDEHYDES EXXON RESEARCH AND ENGINEERING CO. (US) 1984-05-29 US disclosed
US-4450299-A ALDEHYDES FROM UNSATURATED ACYCLIC HYDROCARBONS, CARBON MONOXIDE AND HYDROGEN EXXON RESEARCH AND ENGINEERING CO. (US) 1984-05-22 US disclosed