SCHEMBL1104435

SCHEMBL1104435

Cn1c(S)nc2nc3ccccc3nc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.42
ALDH1A1 P00352 8/20 0.42
MEN1 O00255 6/20 0.40
KMT2A Q03164 6/20 0.40
HCRTR1 O43613 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HPGD P15428 7/20 0.39
GAA P10253 6/20 0.39
MAPT P10636 5/20 0.39
GLA P06280 4/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
NR1I2 O75469 1/20 0.39
AHR P35869 1/20 0.39
HSD17B10 Q99714 5/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104436 0.80 KDM4E (0.46) KDM4EALDH1A1MEN1KMT2AHCRTR1
SCHEMBL110723 0.69 SMN1; SMN2 (0.61) KDM4EALDH1A1MEN1KMT2ANPC1
SCHEMBL11011805 0.69 RAB9A (0.46) KDM4EALDH1A1MEN1KMT2ANPC1
SCHEMBL10270622 0.69 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHCRTR1
SCHEMBL5305100 0.68 TLR7 (0.50) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL375177 0.68 SMN1; SMN2 (0.59) KDM4EALDH1A1MEN1KMT2ANPC1
Methane SCHEMBL4160895 0.68 SMN1; SMN2 (0.59) KDM4EALDH1A1MEN1KMT2ANPC1
Fluoride SCHEMBL31379741 0.68 ATM (0.60) KDM4EALDH1A1MEN1KMT2ANPC1
SCHEMBL13852975 0.67 MAPT (0.43) KDM4EALDH1A1MEN1KMT2ANPC1
SCHEMBL7092051 0.67 GRM5 (0.40) KDM4EALDH1A1MEN1KMT2AHCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 US disclosed
US-20110168044-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-07-14 US disclosed
US-20110091814-A1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-7923197-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-04-12 US disclosed
US-20110020751-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRODUCTION PROCESS OF LITHOGRAPHIC PRINTING PLATE USING THE PRECURSOR FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110017084-A1 IMMERSION TYPE AUTOMATIC DEVELOPING APPARATUS FOR LITHOGRAPHIC PRINTING PLATE AND AUTOMATIC DEVELOPING METHOD FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20080268372-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
US-20080261153-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
US-20080241739-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080160451-A1 METHOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20070231745-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070212641-A1 Lithographic printing plate precursor and method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed