Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692454 | 0.93 | KEAP1 (0.64) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL10063772 | 0.84 | — | — | |
| SCHEMBL1998867 | 0.84 | KEAP1 (0.71) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL7239607 | 0.84 | KEAP1 (0.71) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| Ammonia Solution, Strong SCHEMBL9400430 | 0.81 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL7103406 | 0.81 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL9738476 | 0.81 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL11609926 | 0.81 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL11222517 | 0.81 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E | |
| SCHEMBL9740021 | 0.81 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984000106-A1 | ANESTHETIC-ANTIPRURITIC N-(3-(4-(3-FLUOROBENZYLOXY)PHENOXY)PROPYL)MORPHOLINE COMPOUNDS, COMPOSITIONS AND USE | STIEFEL LABORATORIES (US) | 1984-01-19 | — | — | WO | disclosed |