Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28446070 | 0.90 | KMT2A (0.53) | KMT2AL3MBTL1TDP1ESR1TP53 | |
| SCHEMBL8507182 | 0.89 | KMT2A (0.61) | KMT2AL3MBTL1TDP1ESR1TP53 | |
| SCHEMBL28289831 | 0.88 | KMT2A (0.51) | KMT2AL3MBTL1TDP1ESR1TP53 | |
| SCHEMBL18582793 | 0.88 | KMT2A (0.51) | KMT2AL3MBTL1TDP1ESR1TP53 | |
| SCHEMBL11040710 | 0.86 | KMT2A (0.50) | KMT2AL3MBTL1TDP1ESR1TP53 | |
| SCHEMBL15200656 | 0.85 | KMT2A (0.49) | KMT2AL3MBTL1TDP1ESR1TP53 | |
| SCHEMBL11575458 | 0.85 | KMT2A (0.49) | KMT2AL3MBTL1TDP1ESR1TP53 | |
| SCHEMBL425251 | 0.84 | KMT2A (0.56) | KMT2AL3MBTL1TDP1ESR1TP53 | |
| SCHEMBL867113 | 0.84 | KMT2A (0.56) | KMT2AL3MBTL1TDP1ESR1TP53 | |
| SCHEMBL11522816 | 0.83 | KMT2A (0.54) | KMT2AL3MBTL1TDP1ESR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040889-B1 | ACTIVATORS FOR ZIEGLER TYPE POLYMERIZATION CATALYSTS | UNIROYAL, INC. (US) | 1984-05-30 | — | — | EP | claimed |
| US-4347159-A | CHLORINATED ESTER OF (TETRAHYDRO)FUROIC ACID | UNIROYAL, INC. (US) | 1982-08-31 | — | — | US | claimed |
| EP-0040889-A1 | Activators for Ziegler type polymerization catalysts | UNIROYAL, INC. (US) | 1981-12-02 | — | — | EP | claimed |
| US-9994539-B2 | Formation of 2,5-furan dicarboxylic acid from aldaric acids | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2018-06-12 | — | — | US | disclosed |
| US-20170305873-A1 | FORMATION OF 2,5-FURAN DICARBOXYLIC ACID FROM ALDARIC ACIDS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2017-10-26 | — | — | US | disclosed |
| US-9701652-B2 | Formation of 2,5-furan dicarboxylic acid from aldaric acids | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170144982-A1 | Formation of 2,5-Furan Dicarboxylic Acid from Aldaric Acids | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2017-05-25 | — | — | US | disclosed |
| EP-0040889-B1 | ACTIVATORS FOR ZIEGLER TYPE POLYMERIZATION CATALYSTS | UNIROYAL, INC. (US) | 1984-05-30 | — | — | EP | disclosed |
| US-4451575-A | Activators for Ziegler type polymerization catalysts using bis(trichloromethyl) sulfone | UNIROYAL, INC. (US) | 1984-05-29 | — | — | US | disclosed |
| US-4347159-A | CHLORINATED ESTER OF (TETRAHYDRO)FUROIC ACID | UNIROYAL, INC. (US) | 1982-08-31 | — | — | US | disclosed |
| EP-0040889-A1 | Activators for Ziegler type polymerization catalysts | UNIROYAL, INC. (US) | 1981-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305873-A1 | FORMATION OF 2,5-FURAN DICARBOXYLIC ACID FROM ALDARIC ACIDS | PGD, DERA, ALDOA | KMT2A 2778/4885L3MBTL1 4485/4885TDP1 1486/4885 |
| US-20170144982-A1 | Formation of 2,5-Furan Dicarboxylic Acid from Aldaric Acids | PGD, DERA, ALDOA | KMT2A 2778/4885L3MBTL1 4485/4885TDP1 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.