SCHEMBL425251

SCHEMBL425251

O=C(O)c1occc1CO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.56
TDP1 Q9NUW8 4/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
ESR1 P03372 1/20 0.47
TP53 P04637 1/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
MAPK1 P28482 1/20 0.47
ESR2 Q92731 1/20 0.47
HSD17B10 Q99714 1/20 0.46
ALOX5 P09917 1/20 0.37
ACLY P53396 1/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
MMP1 P03956 1/20 0.33
MMP3 P08254 1/20 0.33
MMP7 P09237 1/20 0.33
MMP9 P14780 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25258823 0.89 TDP1 (0.50) KMT2ATDP1L3MBTL1ESR1TP53
SCHEMBL3953309 0.86 KMT2A (0.45) KMT2ATDP1L3MBTL1ESR1TP53
SCHEMBL11044495 0.84 KMT2A (0.62) KMT2ATDP1L3MBTL1ESR1TP53
SCHEMBL28446070 0.83 KMT2A (0.53) KMT2ATDP1L3MBTL1ESR1TP53
SCHEMBL867113 0.83 KMT2A (0.56) KMT2ATDP1L3MBTL1ESR1TP53
SCHEMBL11522816 0.81 KMT2A (0.54) KMT2ATDP1L3MBTL1ESR1TP53
SCHEMBL6848551 0.81 KMT2A (0.54) KMT2ATDP1L3MBTL1ESR1TP53
SCHEMBL28299997 0.81 KMT2A (0.39) KMT2ATDP1L3MBTL1ESR1TP53
SCHEMBL5552438 0.81 KMT2A (0.54) KMT2ATDP1L3MBTL1ESR1TP53
SCHEMBL12611250 0.81 KMT2A (0.54) KMT2ATDP1L3MBTL1ESR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197367-A1 PROCESS FOR THE OXIDATION OF HYDROXYMETHYLFURFURAL Südzucker AG (DE) 2025-06-19 US claimed
US-20250136566-A1 FURAN DICARBOXYLIC ACID COMPOUND, METHOD FOR PREPARING FURAN DICARBOXYLIC ACID COMPOUND, POLYESTER, AND MEHTOD FOR PREPARING POLYESTER KOLON INDUSTRIES, INC. (KR) 2025-05-01 US claimed
EP-4438599-A1 FURANDICARBOXYLIC ACID COMPOUND, METHOD FOR PRODUCING FURANDICARBOXYLIC ACID COMPOUND, POLYESTER, AND METHOD FOR PRODUCING POLYESTER Kolon Industries, Inc. (KR) 2024-10-02 EP claimed
CN-118679152-A Method for oxidizing hydroxymethylfurfural 祖德楚克尔股份公司 2024-09-20 CN claimed
WO-2024176084-A1 OXIDATION METHOD WITH REDUCED CARBON DIOXIDE EMISSON STORA ENSO OYJ (FI) 2024-08-29 WO claimed
US-12049456-B2 Purified 2,5-furandicarboxylic acid pathway products STORA ENSO OYJ (FI) 2024-07-30 US claimed
CN-118234714-A Furandicarboxylic acid compound, method for producing furandicarboxylic acid compound, polyester, and method for producing polyester 可隆工业株式会社 2024-06-21 CN claimed
CN-116751824-A Method for catalyzing conversion of HMF to generate FDCA through multienzyme cascade reaction 湖北大学 2023-09-15 CN claimed
WO-2023156668-A1 PROCESS FOR THE OXIDATION OF HYDROXYMETHYLFURFURAL Südzucker AG (DE) 2023-08-24 WO claimed
WO-2023128498-A1 FURANDICARBOXYLIC ACID COMPOUND, METHOD FOR PRODUCING FURANDICARBOXYLIC ACID COMPOUND, POLYESTER, AND METHOD FOR PRODUCING POLYESTER 코오롱인더스트리 주식회사 2023-07-06 WO claimed
WO-2019014382-A1 PURIFIED 2,5-FURANDICARBOXYLIC ACID PATHWAY PRODUCTS STORA ENSO OYJ (FI) 2019-01-17 WO claimed
EP-3402787-A1 PROCESSES FOR THE PREPARATION OF 2,5-FURANDICARBOXYLIC ACID AND INTERMEDIATES AND DERIVATIVES THEREOF Stora Enso Oyj (FI) 2018-11-21 EP claimed
EP-3307764-A1 PROCESSES FOR THE FORMATION OF FURANDICARBOXYLIC ACID (FDCA) VIA A MULTISTEP BIOCATALYTIC OXIDATION REACTION OF 5-HYDROXYMETHYLFURFURAL (HMF) Biome Bioplastics Limited (GB) 2018-04-18 EP claimed
WO-2017123763-A1 PROCESSES FOR THE PREPARATION OF 2,5-FURANDICARBOXYLIC ACID AND INTERMEDIATES AND DERIVATIVES THEREOF RENNOVIA INC. (US) 2017-07-20 WO claimed
WO-2016202858-A1 PROCESSES FOR THE FORMATION OF FURANDICARBOXYLIC ACID (FDCA) VIA A MULTISTEP BIOCATALYTIC OXIDATION REACTION OF 5-HYDROXYMETHYLFURFURAL (HMF) BIOME BIOPLASTICS LIMITED (GB) 2016-12-22 WO claimed
US-9487602-B2 Furan based resin, process for the preparation thereof, and use of the compound DSM IP ASSETS B.V. (NL) 2016-11-08 US claimed
US-20130109822-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2013-05-02 US claimed
US-20110021740-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2011-01-27 US claimed
EP-2222656-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP Assets B.V. (NL) 2010-09-01 EP claimed
WO-2009077587-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2009-06-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12049456-B2 Purified 2,5-furandicarboxylic acid pathway products FDPS, HPD, FLAD1 KMT2A 3987/4885TDP1 834/4885L3MBTL1 4882/4885
US-20250136566-A1 FURAN DICARBOXYLIC ACID COMPOUND, METHOD FOR PREPARING FURAN DICARBOXYLIC ACID COMPOUND, POLYESTER, AND MEHTOD FOR PREPARING POLYESTER HADH, DHODH, HAAO KMT2A 940/4885TDP1 3910/4885L3MBTL1 4627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.