Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048795 | 0.89 | TDP1 (0.45) | SIRT5SMN1; SMN2MAPTPKMTDP1 | |
| SCHEMBL11045778 | 0.85 | GLA (0.42) | SIRT5SMN1; SMN2MAPTPOLBPKM | |
| SCHEMBL11046423 | 0.84 | MAPT (0.52) | SIRT5SMN1; SMN2MAPTPOLBLMNA | |
| SCHEMBL128166 | 0.83 | TSHR (0.45) | SMN1; SMN2MAPTPOLBLMNAMAPK1 | |
| SCHEMBL10666174 | 0.81 | MAPT (0.46) | HCAR3SMN1; SMN2MAPTPOLBPKM | |
| SCHEMBL762553 | 0.81 | SMN1; SMN2 (0.60) | SIRT5HCAR3SMN1; SMN2MAPTPOLB | |
| SCHEMBL109574 | 0.79 | ALDH1A1 (0.51) | HCAR3SMN1; SMN2MAPTPOLBPKM | |
| SCHEMBL29392841 | 0.79 | ALDH1A1 (0.51) | HCAR3SMN1; SMN2MAPTPOLBPKM | |
| SCHEMBL9269272 | 0.78 | TSHR (0.48) | SMN1; SMN2MAPTLMNAMAPK1TSHR | |
| SCHEMBL5455930 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTLMNAMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432769-A | MADE BY REACTING 3-AMINO-4-NITRO-CHLOROBENZENE WITH GLYCEROL | L'OREAL (FR) | 1984-02-21 | — | — | US | claimed |
| US-4432769-A | MADE BY REACTING 3-AMINO-4-NITRO-CHLOROBENZENE WITH GLYCEROL | L'OREAL (FR) | 1984-02-21 | — | — | US | disclosed |