Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109574 | 0.90 | ALDH1A1 (0.51) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL29392841 | 0.90 | ALDH1A1 (0.51) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL11045778 | 0.89 | GLA (0.42) | TSHRMAPTLMNASIRT5ALDH1A1 | |
| SCHEMBL11044515 | 0.89 | SIRT5 (0.52) | TDP1TSHRMAPTLMNASIRT5 | |
| SCHEMBL11046423 | 0.86 | MAPT (0.52) | TSHRMAPTLMNASIRT5ALDH1A1 | |
| SCHEMBL128166 | 0.85 | TSHR (0.45) | TSHRMAPTLMNAALDH1A1GAA | |
| SCHEMBL9269272 | 0.82 | TSHR (0.48) | TSHRMAPTLMNAALDH1A1GAA | |
| SCHEMBL2840702 | 0.80 | TDP1 (0.52) | TDP1TSHRMAPTLMNASIRT5 | |
| SCHEMBL8948327 | 0.80 | ALDH1A1 (0.53) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL10580319 | 0.79 | MAPT (0.58) | TDP1TSHRMAPTLMNASIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432769-A | MADE BY REACTING 3-AMINO-4-NITRO-CHLOROBENZENE WITH GLYCEROL | L'OREAL (FR) | 1984-02-21 | — | — | US | claimed |
| US-4432769-A | MADE BY REACTING 3-AMINO-4-NITRO-CHLOROBENZENE WITH GLYCEROL | L'OREAL (FR) | 1984-02-21 | — | — | US | disclosed |