Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | ADK | P55263 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805743 | 0.76 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1LMNASMN1; SMN2KDM4E | |
| SCHEMBL376808 | 0.67 | HSP90AA1 (0.32) | HSP90AA1ESR2TDP1 | |
| SCHEMBL2776999 | 0.66 | — | — | |
| SCHEMBL17979577 | 0.65 | — | — | |
| Water SCHEMBL10703278 | 0.65 | HSP90AA1 (0.31) | HSP90AA1ESR2TDP1 | |
| SCHEMBL28198990 | 0.65 | LMNA (0.34) | LMNAKDM4EGLAGAAACHE | |
| SCHEMBL11012742 | 0.64 | KDM4E (0.32) | KDM4E | |
| SCHEMBL11262568 | 0.64 | KDM4E (0.32) | ALDH1A1KDM4EHPGD | |
| SCHEMBL11526298 | 0.64 | LMNA (0.33) | LMNAACHE | |
| SCHEMBL9621256 | 0.64 | SMN1; SMN2 (0.38) | ALDH1A1LMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032916-A1 | DI-CYANO-GUANIDINES | Société de Recherches et de Synthèses Organiques SA (CH) | 1981-08-05 | — | — | EP | claimed |
| EP-0024393-A1 | IMINO-ALKYL AND AMINO-NITRYL CYANO-GUANIDINES | Société de Recherches et de Synthèses Organiques SA (CH) | 1981-03-11 | — | — | EP | claimed |
| WO-1981000405-A1 | DI-CYANO-GUANIDINES | RECH SYNTHESES ORGAN (CH) | 1981-02-19 | — | — | WO | claimed |
| WO-1980001694-A1 | IMINO-ALKYL AND AMINO-NITRYL CYANO-GUANIDINZE | RECH SYNTHESES ORGAN (CH) | 1980-08-21 | — | — | WO | claimed |
| US-4443613-A | HISTAMINE ANTOGONIST, ANTISECRETORY, ANTIULCER | BAUDET PIERRE J (CH) | 1984-04-17 | — | — | US | disclosed |
| US-4383115-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS | BAUDET PIERRE J (CH) | 1983-05-10 | — | — | US | disclosed |
| EP-0032916-A1 | DI-CYANO-GUANIDINES | Société de Recherches et de Synthèses Organiques SA (CH) | 1981-08-05 | — | — | EP | disclosed |
| EP-0032143-A1 | IMINO-ALKYL AND AMINO-NITRIL CYANO-GUANIDINES | Société de Recherches et de Synthèses Organiques SA (CH) | 1981-07-22 | — | — | EP | disclosed |
| EP-0024393-A1 | IMINO-ALKYL AND AMINO-NITRYL CYANO-GUANIDINES | Société de Recherches et de Synthèses Organiques SA (CH) | 1981-03-11 | — | — | EP | disclosed |
| WO-1981000405-A1 | DI-CYANO-GUANIDINES | RECH SYNTHESES ORGAN (CH) | 1981-02-19 | — | — | WO | disclosed |
| WO-1981000255-A1 | IMINO-ALKYL AND AMINO-NITRIL CYANO-GUANIDINES | RECH SYNTHESES ORGAN (CH) | 1981-02-05 | — | — | WO | disclosed |
| WO-1980001694-A1 | IMINO-ALKYL AND AMINO-NITRYL CYANO-GUANIDINZE | RECH SYNTHESES ORGAN (CH) | 1980-08-21 | — | — | WO | disclosed |