⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL25270175 | 0.91 | PLG (0.71) | — | |
| Oxalic Acid SCHEMBL736575 | 0.88 | PLG (0.68) | — | |
| Glycine SCHEMBL4664011 | 0.86 | PLG (0.65) | — | |
| Acetic Acid SCHEMBL5502506 | 0.86 | — | — | |
| SCHEMBL3465799 | 0.81 | PLG (0.67) | — | |
| SCHEMBL17743478 | 0.81 | PLG (0.54) | — | |
| SCHEMBL10341442 | 0.81 | PLG (0.60) | — | |
| SCHEMBL14416203 | 0.81 | PLG (0.60) | — | |
| SCHEMBL10489690 | 0.81 | PLG (0.67) | — | |
| SCHEMBL8890636 | 0.81 | PLG (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014009767-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF 1-ARYL 2-AMINOMETHYL CYCLOPROPANE CARBOXYAMIDE (Z) DERIVATIVES, THEIR ISOMERS AND SALTS | MICRO LABS LIMITED (IN) | 2014-01-16 | — | — | WO | disclosed |
| US-4478836-A | 1-Aryl 2-aminomethyl cyclopropane carboxyamide (Z) derivatives and their use as useful drugs in the treatment of disturbances of the central nervous system | PIERRE FABRE S.A. (FR) | 1984-10-23 | — | — | US | disclosed |