SCHEMBL10489690

SCHEMBL10489690

NC[C@H]1CC[C@@H](C(N)=O)CC1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLG P00747 1/20 0.67
PLAT P00750 1/20 0.67
LMNA P02545 1/20 0.67
SMN1; SMN2 Q16637 2/20 0.43
CYP2D6 P10635 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
GAA P10253 1/20 0.38
F2 P00734 1/20 0.38
ALOX5 P09917 1/20 0.38
NCF1 P14598 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
ITGB3 P05106 1/20 0.35
ITGA2B P08514 1/20 0.35
ANPEP P15144 1/20 0.34
ENPEP Q07075 1/20 0.34
TSHR P16473 1/20 0.33
KDM1A O60341 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1655177 1.00 PLG (0.67) PLGPLATLMNASMN1; SMN2CYP2D6
SCHEMBL3465799 1.00 PLG (0.67) PLGPLATLMNASMN1; SMN2CYP2D6
Hydrochloric Acid SCHEMBL8595447 0.98 PLG (0.64) PLGPLATLMNASMN1; SMN2CYP2D6
Hydrochloric Acid SCHEMBL8595452 0.98 PLG (0.64) PLGPLATLMNASMN1; SMN2CYP2D6
SCHEMBL3629440 0.86 PLG (0.56) PLGPLATLMNASMN1; SMN2CYP2D6
Carbamic Acid SCHEMBL11044735 0.81
SCHEMBL8897842 0.81 LMNA (0.45) PLGPLATLMNASMN1; SMN2CYP2D6
Cyclopropanecarboxylic Acid Amide SCHEMBL6927157 0.81 SMN1; SMN2 (0.50) PLGPLATLMNASMN1; SMN2CYP2D6
Cyclopropanecarboxylic Acid Amide SCHEMBL5661 0.81
SCHEMBL9797557 0.81 SMN1; SMN2 (0.50) PLGPLATLMNASMN1; SMN2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1026542-A None JP disclosed
JP-S6426542-A 4-AMINOMETHYLCYCLOHEXANECARBOXYLIC ACID AMIDE AND ACID ADDITION SALT THEREOF ASAHI CHEMICAL IND 1989-01-27 JP disclosed