Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.67 |
| ▸ | PLAT | P00750 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489690 | 1.00 | PLG (0.67) | PLGPLATLMNASMN1; SMN2CYP2D6 | |
| SCHEMBL1655177 | 1.00 | PLG (0.67) | PLGPLATLMNASMN1; SMN2CYP2D6 | |
| Hydrochloric Acid SCHEMBL8595447 | 0.98 | PLG (0.64) | PLGPLATLMNASMN1; SMN2CYP2D6 | |
| Hydrochloric Acid SCHEMBL8595452 | 0.98 | PLG (0.64) | PLGPLATLMNASMN1; SMN2CYP2D6 | |
| SCHEMBL3629440 | 0.86 | PLG (0.56) | PLGPLATLMNASMN1; SMN2CYP2D6 | |
| Carbamic Acid SCHEMBL11044735 | 0.81 | — | — | |
| SCHEMBL8897842 | 0.81 | LMNA (0.45) | PLGPLATLMNASMN1; SMN2CYP2D6 | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL6927157 | 0.81 | SMN1; SMN2 (0.50) | PLGPLATLMNASMN1; SMN2CYP2D6 | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL5661 | 0.81 | — | — | |
| SCHEMBL9797557 | 0.81 | SMN1; SMN2 (0.50) | PLGPLATLMNASMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264411-A1 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-10-22 | — | — | US | claimed |
| JP-1083056-A | — | — | None | — | — | JP | disclosed |
| JP-9255542-A | — | — | None | — | — | JP | disclosed |
| JP-9255521-A | — | — | None | — | — | JP | disclosed |
| JP-6072843-A | — | — | None | — | — | JP | disclosed |
| JP-2025417-A | — | — | None | — | — | JP | disclosed |
| JP-6087810-A | — | — | None | — | — | JP | disclosed |
| JP-1026542-A | — | — | None | — | — | JP | disclosed |
| US-20210393809-A1 | LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PSMA-EXPRESSING CANCERS | Universität Heidelbert (DE) | 2021-12-23 | — | — | US | disclosed |
| CN-113631144-A | Cosmetic containing ultraviolet wavelength conversion substance and medicinal agent | 株式会社资生堂 | 2021-11-09 | — | — | CN | disclosed |
| WO-1997046250-A1 | METHODS OF MODIFYING FEEDING BEHAVIOR, COMPOUNDS USEFUL IN SUCH METHODS, AND DNA ENCODING A HYPOTHALAMIC ATYPICAL NEUROPEPTIDE Y/PEPTIDE YY RECEPTOR (Y5) | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-12-11 | — | — | WO | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| JP-H09255542-A | COMPOSITION FOR ORAL CAVITY APPLICATION | SHISEIDO CO LTD | 1997-09-30 | — | — | JP | disclosed |
| JP-H09255521-A | SEBUM SUPPRESSING AGENT | SHISEIDO CO LTD | 1997-09-30 | — | — | JP | disclosed |
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |
| JP-H0687810-A | 4-@(3754/24)AMINOMETHYL)CYCLOHEXANECARBOXAMIDE DERIVATIVE | SUNTORY LTD | 1994-03-29 | — | — | JP | disclosed |
| JP-H0672843-A | SKIN EXTERNAL PREPARATION | SHISEIDO CO LTD | 1994-03-15 | — | — | JP | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |
| JP-H0225417-A | ANTITUMOR AGENT | ASAHI CHEM IND CO LTD | 1990-01-26 | — | — | JP | disclosed |
| JP-S6426542-A | 4-AMINOMETHYLCYCLOHEXANECARBOXYLIC ACID AMIDE AND ACID ADDITION SALT THEREOF | ASAHI CHEMICAL IND | 1989-01-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264411-A1 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | MAPK15, MOK, MAPK14 | PLG 3922/4885PLAT 3066/4885LMNA 4755/4885 |
| US-20210393809-A1 | LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PSMA-EXPRESSING CANCERS | KLK3, PSMA3, FOLH1 | PLG 2410/4885PLAT 1232/4885LMNA 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.