Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808788 | 0.91 | LMNA (0.47) | TSHRL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5807041 | 0.84 | SMN1; SMN2 (0.60) | TSHRL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10525505 | 0.83 | TSHR (0.51) | TSHRTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL4459514 | 0.83 | TSHR (0.51) | TSHRTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL9078631 | 0.79 | TDP1 (0.50) | TSHRTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL5353769 | 0.78 | ALDH1A1 (0.51) | TSHRL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5809076 | 0.78 | ESR1 (0.49) | TSHRTDP1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6717574 | 0.78 | TSHR (0.49) | TSHRTDP1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL6908413 | 0.77 | LMNA (0.40) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL817611 | 0.76 | NPC1 (0.59) | TSHRL3MBTL1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439524-A | Stereoselective resolution of phenylglycine derivatives with enzyme resins | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-27 | — | — | US | disclosed |