Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | ELANE | P08246 | 1/20 | 0.71 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.71 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.68 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314038 | 0.88 | F10 (0.77) | F10TSHRKDM4EHSD17B10HDAC3 | |
| SCHEMBL14338416 | 0.88 | F10 (0.77) | F10HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11665959 | 0.87 | TSHR (0.77) | TSHRKDM4EHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL6349025 | 0.87 | ELANE (0.70) | F10TSHRKDM4EHSD17B10CYP1A2 | |
| SCHEMBL4203434 | 0.86 | TSHR (0.76) | TSHRKDM4EHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL9339256 | 0.86 | TSHR (0.76) | TSHRKDM4EHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL7315643 | 0.86 | HDAC1 (0.64) | F10TSHRKDM4EHSD17B10CYP1A2 | |
| SCHEMBL28439421 | 0.85 | F10 (0.72) | F10TSHRKDM4EHSD17B10HDAC3 | |
| SCHEMBL14855681 | 0.85 | F10 (0.72) | F10HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9002518 | 0.85 | F10 (0.72) | F10KDM4EHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552065-B2 | Biarylamide derivative and compositions containing the derivative as an active ingredient | CATHOLIC UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) | 2013-10-08 | — | — | US | disclosed |
| US-8552065-B2 | Biarylamide derivative and compositions containing the derivative as an active ingredient | CATHOLIC UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) | 2013-10-08 | — | — | US | disclosed |
| US-20120289595-A1 | NOVEL BIARYLAMIDE DERIVATIVE AND COMPOSITIONS CONTAINING THE DERIVATIVE AS AN ACTIVE INGREDIENT | CATHOLIC UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) | 2012-11-15 | — | — | US | disclosed |
| US-20120289595-A1 | NOVEL BIARYLAMIDE DERIVATIVE AND COMPOSITIONS CONTAINING THE DERIVATIVE AS AN ACTIVE INGREDIENT | CATHOLIC UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) | 2012-11-15 | — | — | US | disclosed |
| US-4454324-A | Process for production of encainide | MEAD JOHNSON & COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| US-4394507-A | Process for production of encainide | MEAD JOHNSON & COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289595-A1 | NOVEL BIARYLAMIDE DERIVATIVE AND COMPOSITIONS CONTAINING THE DERIVATIVE AS AN ACTIVE INGREDIENT | TYR, MITF, MC1R | F10 3827/4885TSHR 3003/4885KDM4E 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.