Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11042950 | 0.89 | GPR183 (0.56) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11040553 | 0.89 | MEN1 (0.62) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| Hydrochloric Acid SCHEMBL11044714 | 0.88 | NR3C1 (0.52) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| Hydrochloric Acid SCHEMBL11042518 | 0.86 | MEN1 (0.55) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11060430 | 0.86 | NR3C1 (0.58) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| Hydrochloric Acid SCHEMBL11042554 | 0.85 | NR3C1 (0.57) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| Hydrochloric Acid SCHEMBL11042174 | 0.85 | SMN1; SMN2 (0.57) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11045220 | 0.82 | SLC6A4 (0.57) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| Hydrochloric Acid SCHEMBL11047745 | 0.82 | ALDH1A1 (0.64) | MEN1LMNATSHRKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11040863 | 0.82 | NR3C1 (0.68) | NR3C1PGRSLC6A4KCNH2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |