SCHEMBL1104522

SCHEMBL1104522

Cc1ccc(Oc2ccc(C(c3ccc(Oc4ccc(N5C(=O)c6ccc(C(c7ccc8c(c7)C(=O)N(C)C8=O)(C(F)(F)F)C(F)(F)F)cc6C5=O)cc4)cc3)(C(F)(F)F)C(F)(F)F)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ALDH1A1 P00352 4/20 0.44
NPC1 O15118 1/20 0.44
TSHR P16473 1/20 0.44
CASP1 P29466 1/20 0.44
RAB9A P51151 1/20 0.44
CASP7 P55210 1/20 0.44
HSD17B10 Q99714 1/20 0.44
BRD4 O60885 1/20 0.42
PKM P14618 1/20 0.41
NPSR1 Q6W5P4 2/20 0.41
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA9 Q16790 6/20 0.41
CA12 O43570 4/20 0.41
CA1 P00915 4/20 0.41
ESR1 P03372 1/20 0.41
CA2 P00918 2/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1962793 0.99 MEN1 (0.47) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL30829232 0.99 MEN1 (0.47) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL25969188 0.95 MEN1 (0.52) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL25969185 0.95 MEN1 (0.52) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL12204981 0.95 MEN1 (0.44) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL12009338 0.95 MEN1 (0.44) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL1960350 0.93 ALDH1A1 (0.50) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL14106915 0.92 BRD4 (0.50) MEN1KMT2AALDH1A1HSD17B10BRD4
SCHEMBL12260131 0.92 ALDH1A1 (0.51) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL25969156 0.91 MEN1 (0.48) MEN1KMT2AALDH1A1NPC1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8154791-B2 Light control film HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-04-10 US disclosed
US-8154791-B2 Light control film HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-04-10 US disclosed
US-8025967-B1 Intermediate transfer member and method of manufacture XEROX CORPORATION (US) 2011-09-27 US disclosed
US-20110188901-A1 INTERMEDIATE TRANSFER MEMBER AND METHOD OF MANUFACTURE XEROX CORPORATION (US) 2011-08-04 US disclosed
US-20110143115-A1 INTERMEDIATE TRANSFER MEMBER AND METHOD OF MANUFACTURE XEROX CORPORATION (US) 2011-06-16 US disclosed
US-20100309544-A1 LIGHT CONTROL FILM GAUZY LTD (IL) 2010-12-09 US disclosed
US-20100309544-A1 LIGHT CONTROL FILM GAUZY LTD (IL) 2010-12-09 US disclosed
US-20090226639-A1 Homeotropic and hybrid bulk alignment of lyotropic chromonic liquid crystals KENT STATE UNIVERSITY 2009-09-10 US disclosed
US-7208109-B2 Changing the solution to nonflowable by absorbing a coagulant, then solvent extraction, for molding a solution of a liquid crystal polymer, polybenzoxazoles or polybenzothiazoles TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-04-24 US disclosed