Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24099564 | 0.89 | SLC6A4 (0.45) | ALDH1A1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL11048069 | 0.85 | SLC6A4 (0.54) | ALDH1A1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL22874622 | 0.82 | TEAD4 (0.57) | ALDH1A1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL2537380 | 0.81 | SLC6A4 (0.49) | ALDH1A1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL14252748 | 0.81 | MAOB (0.46) | ALDH1A1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL22874539 | 0.79 | MAPT (0.40) | SLC6A4SLC6A2SLC6A3HTR1AMAPT | |
| SCHEMBL5371133 | 0.79 | SLC6A4 (0.45) | ALDH1A1SLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL10543538 | 0.79 | MAPT (0.38) | ALDH1A1SLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL18615345 | 0.78 | AR (0.55) | ALDH1A1SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL22874627 | 0.78 | LMNA (0.48) | ALDH1A1SLC6A4SLC6A2SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045423-B1 | PROCESS FOR THE ALPHA-HALOGENATION OF POSSIBLY SUBSTITUTED METHYL AROMATICS | BAYER AG (DE) | 1984-02-22 | — | — | EP | disclosed |
| EP-0045423-A1 | Process for the alpha-halogenation of possibly substituted methyl aromatics | BAYER AG (DE) | 1982-02-10 | — | — | EP | disclosed |