Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048069 | 0.92 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3HTR1AHTR2A | |
| SCHEMBL11045858 | 0.89 | ALDH1A1 (0.41) | SLC6A4SLC6A2SLC6A3HTR1AHTR2A | |
| SCHEMBL22874622 | 0.89 | TEAD4 (0.57) | SLC6A4SLC6A2SLC6A3HTR1ATEAD4 | |
| SCHEMBL22874627 | 0.88 | LMNA (0.48) | SLC6A4SLC6A2SLC6A3HTR1ATEAD4 | |
| SCHEMBL2537380 | 0.88 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HTR1AHTR2A | |
| SCHEMBL22874539 | 0.86 | MAPT (0.40) | SLC6A4SLC6A2SLC6A3HTR1AHTR2A | |
| SCHEMBL10548072 | 0.85 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3HTR1ATEAD4 | |
| SCHEMBL18615345 | 0.84 | AR (0.55) | SLC6A4SLC6A2SLC6A3HTR1AALDH1A1 | |
| SCHEMBL22199022 | 0.83 | HSPB1 (0.45) | SLC6A4SLC6A2SLC6A3HTR1ATEAD4 | |
| SCHEMBL25906312 | 0.82 | TSHR (0.45) | SLC6A4TEAD4HTR2AKCNH2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3760633-B1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2021-12-15 | — | — | EP | disclosed |