Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016773 | 0.89 | TSHR (0.46) | TSHRFAAHTRPV1HIF1AUSP2 | |
| SCHEMBL2494420 | 0.89 | TSHR (0.46) | TSHRFAAHTRPV1HIF1AUSP2 | |
| SCHEMBL1008818 | 0.89 | TSHR (0.46) | TSHRFAAHTRPV1HIF1AUSP2 | |
| SCHEMBL1367335 | 0.87 | TSHR (0.42) | TSHRFAAHTRPV1HIF1A | |
| SCHEMBL198865 | 0.80 | HIF1A (0.43) | TSHRFAAHTRPV1HIF1A | |
| SCHEMBL11042234 | 0.78 | TSHR (0.50) | TSHRFAAHTRPV1HIF1A | |
| SCHEMBL24674166 | 0.76 | RAB9A (0.31) | — | |
| SCHEMBL10081548 | 0.76 | USP2 (0.35) | USP2 | |
| SCHEMBL10081549 | 0.76 | RAB9A (0.31) | — | |
| SCHEMBL24587941 | 0.73 | TSHR (0.41) | TSHRFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065319-B1 | PROCESS FOR THE PREPARATION OF AN UNSATURATED MACROCYCLIC KETONE | FIRMENICH SA (CH) | 1984-10-17 | — | — | EP | disclosed |