Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104566 | 0.90 | ATM (0.48) | ATMMEN1KMT2APOLBCACNA1B | |
| SCHEMBL1104567 | 0.84 | ATM (0.40) | ATMMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL13325754 | 0.83 | ATM (0.39) | ATMMEN1KMT2APOLBCACNA1B | |
| SCHEMBL15085996 | 0.81 | ATM (0.59) | ATMMEN1KMT2APOLBCACNA1B | |
| SCHEMBL905973 | 0.78 | ATM (0.59) | ATMMEN1KMT2APOLBCACNA1B | |
| SCHEMBL19691980 | 0.78 | ATM (0.59) | ATMMEN1KMT2APOLBCACNA1B | |
| SCHEMBL25771053 | 0.77 | ATM (0.54) | ATMMEN1KMT2APOLBCACNA1B | |
| SCHEMBL1104576 | 0.77 | ALDH1A1 (0.44) | ATMCACNA1BAPBA1ALDH1A1TSHR | |
| SCHEMBL1104598 | 0.75 | ATM (0.51) | ATMMEN1KMT2APOLBCACNA1B | |
| SCHEMBL16358149 | 0.75 | ATM (0.39) | ATMMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153725-B2 | Supports for oligomer synthesis | ISIS PHARMACEUTICALS, INC (US) | 2012-04-10 | — | — | US | disclosed |