Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048900 | 0.82 | CXCL12 (0.50) | MAPTHPGDHTTMEN1KMT2A | |
| SCHEMBL8629565 | 0.74 | POLB (0.50) | KAT8MAPTHPGDHTTMEN1 | |
| SCHEMBL8078405 | 0.72 | KAT8 (0.81) | KAT8SIRT5MAPTMEN1KMT2A | |
| SCHEMBL443203 | 0.72 | KAT8 (0.81) | KAT8SIRT5MAPTMEN1KMT2A | |
| SCHEMBL420591 | 0.72 | KAT8 (0.81) | KAT8SIRT5MAPTMEN1KMT2A | |
| SCHEMBL14158871 | 0.68 | MAPT (0.46) | MAPTHPGDHTTCA2CA12 | |
| SCHEMBL2449699 | 0.64 | CA2 (0.73) | MAPTHPGDMEN1KMT2ACA2 | |
| SCHEMBL2449700 | 0.64 | CA2 (0.73) | MAPTHPGDMEN1KMT2ACA2 | |
| SCHEMBL901098 | 0.64 | ESR1 (0.78) | CA2CA12CA1CA3TYR | |
| SCHEMBL901029 | 0.64 | ESR1 (0.78) | CA2CA12CA1CA3TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021513-B1 | PHOTOGRAPHIC SILVER HALIDE MATERIALS CONTAINING DISPERSED LIGHT-ABSORBING MEROSTYRYL DYES | AGFA-GEVAERT N.V. (BE) | 1984-03-21 | — | — | EP | claimed |