SCHEMBL8629565

SCHEMBL8629565

CC1=NN(c2ccc(C(=O)O)cc2)CC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.50
ALDH1A1 P00352 5/20 0.46
KMT2A Q03164 4/20 0.46
TDP1 Q9NUW8 3/20 0.46
MEN1 O00255 3/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 1/20 0.46
APEX1 P27695 1/20 0.46
CA12 O43570 3/20 0.45
CA9 Q16790 3/20 0.45
CA1 P00915 2/20 0.45
KAT8 Q9H7Z6 3/20 0.44
DDAH1 O94760 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HTT P42858 1/20 0.41
USP2 O75604 2/20 0.41
EP300 Q09472 2/20 0.40
MAPK1 P28482 1/20 0.40
PTGS2 P35354 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9510339 0.84 NR4A1 (0.45) POLBALDH1A1KMT2ATDP1MEN1
SCHEMBL9805803 0.82 KMT2A (0.51) POLBALDH1A1KMT2ATDP1MEN1
SCHEMBL9512623 0.81 POLB (0.44) POLBALDH1A1KMT2ATDP1MEN1
SCHEMBL7786530 0.81 F2 (0.42) ALDH1A1KMT2ATDP1MEN1MAPT
SCHEMBL5425655 0.80 MAPT (0.43) POLBALDH1A1KMT2ATDP1MEN1
SCHEMBL11293395 0.77 MAPT (0.50) POLBALDH1A1KMT2ATDP1MEN1
SCHEMBL9309242 0.76 KAT8 (0.41) ALDH1A1KMT2ATDP1MEN1KDM4E
SCHEMBL11046037 0.74 KAT8 (0.44) POLBALDH1A1KMT2ATDP1MEN1
SCHEMBL643536 0.68 POLB (0.75) POLBALDH1A1KMT2ATDP1MEN1
SCHEMBL13377436 0.67 KAT8 (0.59) POLBALDH1A1KMT2ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0549486-B1 Microprecipitated methine oxonol filter dye dispersions EASTMAN KODAK CO (US) 1998-07-15 EP disclosed
US-5326687-A Photographic silver halide element containing microprecipitated methine oxonol filter dye dispersions EASTMAN KODAK COMPANY (US) 1994-07-05 US disclosed
EP-0299435-B1 Photographic oxonol colour filter dyes EASTMAN KODAK CO (US) 1994-06-01 EP disclosed
US-5274109-A A pyrazole-based cyanine dye EASTMAN KODAK COMPANY (US) 1993-12-28 US disclosed
EP-0323729-B1 SOLID PARTICLE DISPERSIONS OF DYES USEFUL IN PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1993-09-29 EP disclosed
EP-0549486-A2 Microprecipitated methine oxonol filter dye dispersions EASTMAN KODAK COMPANY (US) 1993-06-30 EP disclosed
EP-0294461-B1 SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-10-23 EP disclosed
EP-0276566-B1 RADIOGRAPHIC ELEMENT EXHIBITING REDUCED CROSSOVER EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-10-24 EP disclosed
US-4948718-A FILTER DYES EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed
US-4900652-A FILM SUPPORT CAPABLE OF TRANSMITTING RADIATION. EASTMAN KODAK COMPANY (US) 1990-02-13 US disclosed
US-4855221-A PHOTOGRAPHIC FILTER IN COLLOIDAL DISPERSION EASTMAN KODAK COMPANY (US) 1989-08-08 US disclosed
EP-0323729-A2 Solid particle dispersions of dyes useful in photographic elements EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-07-12 EP disclosed
US-4803150-A MICROCRYSTALLINE DYE PARTICLES EASTMAN KODAK COMPANY (US) 1989-02-07 US disclosed
EP-0299435-A2 Photographic oxonol colour filter dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-01-18 EP disclosed
EP-0294461-A1 SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS. EASTMAN KODAK CO (US) 1988-12-14 EP disclosed
EP-0276566-A1 Radiographic element exhibiting reduced crossover EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-08-03 EP disclosed
WO-1988004794-A1 SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1988-06-30 WO disclosed