Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3152073 | 0.78 | SMN1; SMN2 (0.42) | MAPTKDM4EALDH1A1FAAHMGLL | |
| SCHEMBL9908789 | 0.78 | MAPT (0.49) | MAPTL3MBTL1KDM4EALDH1A1GLA | |
| SCHEMBL1426445 | 0.70 | F2 (0.39) | MAPTALDH1A1LMNAMGLL | |
| SCHEMBL14660249 | 0.70 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1GLAHTT | |
| SCHEMBL11167868 | 0.67 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1HTTFAAH | |
| SCHEMBL7483484 | 0.67 | MEN1 (0.43) | MAPTALDH1A1HTTFAAHLMNA | |
| SCHEMBL7483124 | 0.67 | MEN1 (0.43) | MAPTALDH1A1HTTFAAHLMNA | |
| SCHEMBL17886074 | 0.66 | MAPT (0.37) | MAPTKDM4EALDH1A1GLAHTT | |
| SCHEMBL13835669 | 0.66 | CYP3A4 (0.48) | MAPTALDH1A1HTTFAAHLMNA | |
| SCHEMBL29064616 | 0.65 | MGLL (0.67) | MAPTALDH1A1HTTFAAHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469692-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | ALKALOIDA VEGYESZETI GYAR (HU) | 1984-09-04 | — | — | US | disclosed |