Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27261402 | 0.76 | DDB1 (0.40) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL22394492 | 0.74 | MAP3K14 (0.41) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL11049674 | 0.73 | CTRB1 (0.33) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL11122420 | 0.73 | MAP3K14 (0.44) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| Bromide SCHEMBL11047216 | 0.72 | CTRB1 (0.33) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL28959677 | 0.72 | MEN1 (0.41) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL6822735 | 0.71 | MAP3K14 (0.39) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL1536268 | 0.69 | MAP3K14 (0.41) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL4418866 | 0.69 | MAP3K14 (0.38) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL22394491 | 0.69 | MAP3K14 (0.38) | MEN1APEX1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465844-A | PEPTIDE, GERMICIDE, DISINFECTANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-08-14 | — | — | US | disclosed |
| US-4436918-A | FROM A 2,5-DIOXOPYRROLIDINE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-03-13 | — | — | US | disclosed |