Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22394492 | 0.75 | MAP3K14 (0.41) | MAP3K14CYP19A1MEN1APEX1KMT2A | |
| SCHEMBL9632941 | 0.72 | — | — | |
| SCHEMBL4418866 | 0.71 | MAP3K14 (0.38) | MAP3K14CYP19A1MEN1APEX1KMT2A | |
| SCHEMBL22394491 | 0.71 | MAP3K14 (0.38) | MAP3K14CYP19A1MEN1APEX1KMT2A | |
| SCHEMBL11046047 | 0.71 | MEN1 (0.39) | MAP3K14MEN1APEX1KMT2ATDP1 | |
| SCHEMBL2956440 | 0.70 | MAP3K14 (0.44) | MAP3K14CYP19A1MEN1APEX1KMT2A | |
| SCHEMBL25905221 | 0.70 | MAP3K14 (0.44) | MAP3K14CYP19A1MEN1APEX1KMT2A | |
| SCHEMBL25905222 | 0.70 | MAP3K14 (0.44) | MAP3K14CYP19A1MEN1APEX1KMT2A | |
| SCHEMBL11122420 | 0.70 | MAP3K14 (0.44) | MAP3K14CYP19A1MEN1APEX1KMT2A | |
| SCHEMBL11063892 | 0.68 | NPC1 (0.36) | MAP3K14CYP19A1MEN1APEX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022536-A1 | NEW HETEROCYCLIC AMIDE COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (US) | 2004-03-18 | — | — | WO | disclosed |