Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042965 | 0.89 | MAPT (0.48) | ALDH1A1MAPTKCNH3HDAC3HDAC4 | |
| SCHEMBL10606669 | 0.87 | ALDH1A1 (0.57) | ALDH1A1MAPTKCNH3HDAC3HDAC4 | |
| SCHEMBL9189703 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTKCNH3HDAC3HDAC4 | |
| SCHEMBL11040887 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPTKCNH3HDAC3HDAC4 | |
| SCHEMBL2255790 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MAPTKCNH3L3MBTL1HTR2A | |
| SCHEMBL28681649 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTKCNH3HDAC3HDAC4 | |
| SCHEMBL9572777 | 0.79 | MAPT (0.44) | ALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL49577 | 0.78 | ALDH1A1 (0.73) | ALDH1A1MAPTKCNH3L3MBTL1 | |
| SCHEMBL20318842 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTKCNH3HDAC3HDAC4 | |
| SCHEMBL16234268 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPTKCNH3HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468526-A | Process for the preparation of thiuram disulfides | AKZONA INCORPORATED (US) | 1984-08-28 | — | — | US | disclosed |