Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046087 | 0.89 | ALDH1A1 (0.55) | MAPTALDH1A1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL9189703 | 0.89 | ALDH1A1 (0.50) | MAPTALDH1A1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL6284685 | 0.86 | MAPT (0.50) | MAPTALDH1A1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL7193484 | 0.84 | ALDH1A1 (0.52) | MAPTALDH1A1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL9572777 | 0.82 | MAPT (0.44) | MAPTALDH1A1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL9572804 | 0.81 | MAPT (0.48) | MAPTALDH1A1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL1848362 | 0.80 | ALDH1A1 (0.47) | MAPTALDH1A1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL17297894 | 0.80 | RAB9A (0.45) | ALDH1A1KMT2ANPC1RAB9APOLB | |
| SCHEMBL1548538 | 0.79 | ALDH1A1 (0.56) | MAPTALDH1A1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL11044866 | 0.79 | ALDH1A1 (0.47) | MAPTALDH1A1L3MBTL1SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468526-A | Process for the preparation of thiuram disulfides | AKZONA INCORPORATED (US) | 1984-08-28 | — | — | US | disclosed |