Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166848 | 0.93 | HSD17B10 (0.69) | HSD17B10CYP1A2KMT2AMEN1RXFP1 | |
| Benzene SCHEMBL15881255 | 0.91 | HSD17B10 (0.67) | HSD17B10CYP1A2KMT2AMEN1RXFP1 | |
| Hydrochloric Acid SCHEMBL8884354 | 0.91 | HSD17B10 (0.67) | HSD17B10CYP1A2KMT2AMEN1RXFP1 | |
| O-Xylene SCHEMBL11044886 | 0.83 | MEN1 (0.59) | HSD17B10KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL13680547 | 0.83 | CNR1 (0.61) | HSD17B10CYP1A2KMT2AMEN1RXFP1 | |
| SCHEMBL27612156 | 0.82 | MEN1 (0.79) | CYP1A2KMT2AMEN1RXFP1KCNK3 | |
| Styrene SCHEMBL9246939 | 0.82 | MAOB (0.58) | HSD17B10CYP1A2KMT2AMEN1RXFP1 | |
| SCHEMBL3690365 | 0.79 | MAPT (0.59) | KMT2AMEN1ALDH1A1KCNK3KCNK9 | |
| SCHEMBL2969536 | 0.79 | CYP3A4 (0.79) | HSD17B10CYP1A2KMT2AMEN1RXFP1 | |
| SCHEMBL533767 | 0.78 | KCNK3 (0.81) | KMT2AMEN1RXFP1ALDH1A1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31550-E | N-(2-Chloro-4-pyridyl) ureas | Shudo, Koichi (JP) | 1984-04-10 | — | — | US | disclosed |