Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CSF1R | P07333 | 1/20 | 0.56 |
| ▸ | FLT1 | P17948 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166848 | 0.89 | HSD17B10 (0.69) | HSD17B10CYP1A2KCNK3KCNH2KCNK9 | |
| SCHEMBL13680497 | 0.88 | KIF11 (0.69) | CNR1CSF1RFLT1FLT3KIF11 | |
| SCHEMBL13749770 | 0.88 | KIF11 (0.69) | CNR1CSF1RFLT1FLT3KIF11 | |
| Hydrochloric Acid SCHEMBL8884354 | 0.87 | HSD17B10 (0.67) | HSD17B10CYP1A2KCNK3KCNH2KCNK9 | |
| Benzene SCHEMBL15881255 | 0.87 | HSD17B10 (0.67) | HSD17B10CYP1A2KCNK3KCNH2KCNK9 | |
| SCHEMBL13681314 | 0.86 | CNR1 (0.65) | CNR1HSD17B10CSF1RFLT1FLT3 | |
| SCHEMBL13680541 | 0.84 | HSD17B10 (0.79) | CNR1HSD17B10CYP1A2MGLLKCNK3 | |
| SCHEMBL30164935 | 0.84 | MGLL (0.72) | CNR1KIF11MGLL | |
| SCHEMBL4082541 | 0.84 | MGLL (0.72) | CNR1KIF11MGLL | |
| O-Xylene SCHEMBL11046097 | 0.83 | HSD17B10 (0.61) | HSD17B10CYP1A2KCNK3KCNH2KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |