SCHEMBL3690365

SCHEMBL3690365

NC(=O)Nc1cccc(NC(N)=O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.59
GAA P10253 1/20 0.59
GFER P55789 1/20 0.59
GPR35 Q9HC97 1/20 0.58
PEPD P12955 1/20 0.54
DDX3X O00571 1/20 0.54
KCNK3 O14649 1/20 0.54
KCNK9 Q9NPC2 1/20 0.54
ALDH1A1 P00352 3/20 0.52
NPC1 O15118 1/20 0.52
KIF11 P52732 1/20 0.51
LPAR1 Q92633 1/20 0.50
LPAR2 Q9HBW0 1/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
TOP1 P11387 1/20 0.48
TOP2A P11388 1/20 0.48
TOP2B Q02880 1/20 0.48
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8350546 0.89 GAA (0.50) MAPTGAAGFERGPR35PEPD
SCHEMBL8532903 0.89 ALDH1A1 (0.67) MAPTALDH1A1MEN1KMT2A
SCHEMBL22699676 0.89 MAPT (0.50) MAPTGAAGFERGPR35PEPD
SCHEMBL17189470 0.88 SIRT1 (0.66) MAPTGAAGFERDDX3XNPC1
SCHEMBL5544315 0.87 MAPT (0.52) MAPTGAAGFERGPR35PEPD
SCHEMBL33716 0.87 DDX3X (0.74) MAPTGAAGFERPEPDDDX3X
SCHEMBL3185695 0.87 KMT2A (0.66) MAPTGAAGFERPEPDALDH1A1
SCHEMBL7564141 0.87 GAA (0.52) MAPTGAAGFERGPR35PEPD
SCHEMBL29521756 0.87 DDX3X (0.74) MAPTGAAGFERPEPDDDX3X
SCHEMBL27392287 0.86 GAA (0.47) MAPTGAAGFERGPR35PEPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960352-A Photosensitive polyimide precursor resin, preparation method thereof and photosensitive resin composition 深圳市道尔顿电子材料有限公司 2023-04-14 CN disclosed
US-11161807-B2 Thermo-thickening compounds for non-polar liquid SORBONNE UNIVERSITE (FR) 2021-11-02 US disclosed
WO-2010069854-A2 MODIFIED POLYOLEFIN WAXES BASF SE (DE) 2010-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11161807-B2 Thermo-thickening compounds for non-polar liquid PUF60, NONO, MAPT MAPT 3/4885GAA 2507/4885GFER 4385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.