SCHEMBL1104617

SCHEMBL1104617

COCCOCCC[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.34
CA2 P00918 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
EPHX2 P34913 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16978083 1.00 ALOX15 (0.34) ALOX15CA2CYP3A4TSHREPHX2
SCHEMBL4226846 1.00 ALOX15 (0.34) ALOX15CA2CYP3A4TSHREPHX2
SCHEMBL9332388 0.87 ALOX15 (0.39) ALOX15TSHR
SCHEMBL16978090 0.85 CA2 (0.32) CA2CYP3A4TSHREPHX2
SCHEMBL30621784 0.84 CA2 (0.34) CA2
SCHEMBL1041150 0.84 CA2 (0.34) CA2
SCHEMBL6971201 0.84
SCHEMBL19319601 0.81 CA2 (0.31) CA2CYP3A4TSHR
SCHEMBL16435867 0.81 CA2 (0.31) CA2CYP3A4TSHR
SCHEMBL15159324 0.81 CA2 (0.31) CA2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9923243-B2 Silicone epoxy ether compositions, methods for making same and uses therefor MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-20 US disclosed
US-9786954-B2 Electrolyte including silane for use in electrochemical devices ORBIA FLUOR & ENERGY MATERIALS USA, INC. 2017-10-10 US disclosed
US-20150050560-A1 SILICONE EPOXY ETHER COMPOSITIONS, METHODS FOR MAKING SAME AND USES THEREFOR MOMENTIVE PERFORMANCE MATERIALS INC. 2015-02-19 US disclosed
US-20140342244-A1 ELECTROLYTE INCLUDING SILANE FOR USE IN ELECTROCHEMICAL DEVICES ORBIA FLUOR & ENERGY MATERIALS USA, INC. 2014-11-20 US disclosed
US-8765295-B2 Electrolyte including silane for use in electrochemical devices WEST ROBERT C (US) 2014-07-01 US disclosed
US-8715863-B2 Battery having electrolyte with mixed solvent QUALLION LLC (US) 2014-05-06 US disclosed
US-20120171578-A1 Battery having electrolyte with mixed solvent QUALLION LLC 2012-07-05 US disclosed
US-20120135313-A1 ELECTROLYTE INCLUDING SILANE FOR USE IN ELECTROCHEMICAL DEVICES WEST ROBERT C (US) 2012-05-31 US disclosed
US-8153307-B1 Battery including electrolyte with mixed solvent QUALLION LLC (US) 2012-04-10 US disclosed
US-7718321-B2 Lithium difluoro oxalatoborate in silane or siloxane is electrolyte; one or more anodes that include two or three components selected from of carbon beads, carbon fibers, and graphite flakes; good discharge capacity retention after formation of a passivation layer QUALLION LLC (US) 2010-05-18 US disclosed
US-7598003-B1 Includes lithium bis[bidentate]borate or lithium dihalo mono[bidentate]borate QUALLION LLC (US) 2009-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120135313-A1 ELECTROLYTE INCLUDING SILANE FOR USE IN ELECTROCHEMICAL DEVICES HCN2, CLCN2, SCNN1A ALOX15 3751/4885CA2 50/4885CYP3A4 2877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.