Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848019 | 0.81 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL467445 | 0.81 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL9453862 | 0.81 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL28968671 | 0.79 | THRB (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL7623072 | 0.79 | THRB (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL29350265 | 0.79 | THRB (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL28768388 | 0.78 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| Ethylene Glycol SCHEMBL10449690 | 0.77 | TSHR (0.53) | TSHRTHRBALDH1A1 | |
| SCHEMBL2641339 | 0.77 | TSHR (0.46) | TSHRTHRBTDP1ALDH1A1 | |
| SCHEMBL3199691 | 0.76 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444831-A | UPHOLSTERY | STAUFFER CHEMICAL COMPANY (US) | 1984-04-24 | — | — | US | disclosed |
| US-4443903-A | AMINOPHOSPHONATE ESTER, AMINO RESIN | STAUFFER CHEMICAL COMPANY (US) | 1984-04-24 | — | — | US | disclosed |
| US-4404313-A | AMINOPHOSPHONATE ESTER | STAUFFER CHEMICAL COMPANY (US) | 1983-09-13 | — | — | US | disclosed |