Methacrylic Acid

Methacrylic Acid

SCHEMBL467445

C=C(C)C(=O)O.C=C(C)C(=O)OCCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.53
TSHR P16473 4/20 0.52
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 2/20 0.41
ACHE P22303 1/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
TGFBR1 P36897 1/20 0.31
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL9453862 1.00 THRB (0.53) THRBTSHRPOLBAPEX1HTT
Methacrylic Acid SCHEMBL29350265 0.98 THRB (0.57) THRBTSHRPOLBAPEX1HTT
Methacrylic Acid SCHEMBL28968671 0.98 THRB (0.52) THRBTSHRPOLBAPEX1HTT
Methacrylic Acid SCHEMBL7623072 0.98 THRB (0.52) THRBTSHRPOLBAPEX1HTT
Acetic Acid SCHEMBL2590428 0.93 THRB (0.55) THRBTSHRPOLBAPEX1HTT
SCHEMBL29229747 0.93 THRB (0.59) THRBTSHRPOLBAPEX1HTT
SCHEMBL6864388 0.93 THRB (0.59) THRBTSHRPOLBAPEX1HTT
SCHEMBL14886 0.93
Methacrylic Acid SCHEMBL1720191 0.92 ALDH1A1 (0.56) THRBTSHRPOLBAPEX1HTT
Triethylene Glycol SCHEMBL8433183 0.92 THRB (0.56) THRBTSHRPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12461280-B2 Comfortable ophthalmic device and methods of its production JOHNSON & JOHNSON VISION CARE, INC. (US) 2025-11-04 US claimed
WO-2025050013-A1 COVALENT POLYMER-NUCLEIC ACID CONJUGATES FOR MODULATION OF THE RIG-I PATHWAY VANDERBILT UNIVERSITY (US) 2025-03-06 WO claimed
CN-119505091-A 3D printing hybrid double-network hydrogel and preparation method and application thereof 东南大学 2025-02-25 CN claimed
CN-118403510-A Polytetrafluoroethylene-based composite nanofiltration membrane and preparation method and application thereof 浙江理工大学 2024-07-30 CN claimed
US-20240142666-A1 COMFORTABLE OPHTHALMIC DEVICE AND METHODS OF ITS PRODUCTION JOHNSON & JOHNSON VISION CARE (US) 2024-05-02 US claimed
US-11953651-B2 Comfortable ophthalmic device and methods of its production JOHNSON & JOHNSON VISION CARE, INC. (US) 2024-04-09 US claimed
CN-117393706-A Composition for coating carbon nanomaterial 卡本新技术有限公司 2024-01-12 CN claimed
US-20230384482-A1 SANDWICH COLORED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-30 US claimed
CN-113663084-B Mesoporous silica prodrug nanoparticle for photothermal therapy and chemotherapy as well as preparation method and application thereof 华南理工大学 2023-11-21 CN claimed
CN-114177896-B Nanometer-micrometer particles with high surface free energy layer and low surface free energy layer, and preparation method and application thereof 中国石油大学(北京) 2023-07-21 CN claimed
WO-2006085898-A1 ARTICLES HAVING BIOACTIVE SURFACES AND SOLVENT-FREE METHODS OF PREPARATION THEREOF BECTON, DICKINSON & COMPANY (US) 2006-08-17 WO claimed
US-20050255327-A1 article comprising glass substrate, wherein glass substrate comprises a hydroxyl-rich polymer layer comprising free reactive groups, an aminopropyltrimethoxysilane (APTMS) layer on top of hydroxyl-rich polymer layer, a biologically functional molecule covalently attached to APTMS layer BECTON, DICKINSON AND COMPANY 2005-11-17 US claimed
US-6627720-B2 Monoethylenically unsaturated monomers are polymerized with at least one multiethylenically unsaturated monomer at high temperatures by free radical polymerization in a continuous reactor, without formation of highly crosslinked gels JOHNSON POLYMER, LLC 2003-09-30 US claimed
US-6265511-B1 BLEND OF DIVINYL MONOMER AND MONOETHYLENICALLY UNSATURATED MONOMER S. C. JOHNSON COMMERICAL MARKETS, INC. 2001-07-24 US claimed
WO-2001040370-A2 IONICALLY CROSSLINKED HYDROGELS WITH ADJUSTABLE GELATION TIME THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2001-06-07 WO claimed
WO-2000055253-A1 IONOMER COMPOSITE COMPOSITIONS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2000-09-21 WO claimed
EP-0534017-A1 Electrophoretic method using an electrophoretic matrix W.R. Grace & Co.-Conn. (US) 1993-03-31 EP claimed
EP-0150674-B1 METHOD OF MAKING THERMOSETTABLE BONDING FILMS CIBA-GEIGY AG (CH) 1987-04-01 EP claimed
US-4612209-A PHOTOPOLYMERIZABLE ACRYLIC ACIDS OR ESTERS AND EPOXYIDE RESIN CIBA-GEIGY CORPORATION (US) 1986-09-16 US claimed
US-RE29693-E Process of soaking and sterilizing hydrophilic soft contact lens with chlorhexidine BARNES-HIND PHARMACEUTICALS, INC. (US) 1978-07-04 US claimed