Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10613587 | 0.79 | — | — | |
| SCHEMBL10620246 | 0.76 | ALDH1A1 (0.32) | ALDH1A1GAA | |
| SCHEMBL13113266 | 0.66 | — | — | |
| SCHEMBL783100 | 0.62 | — | — | |
| SCHEMBL13557089 | 0.61 | ALDH1A1 (0.65) | ALDH1A1LMNASRD5A2HPGDHTT | |
| SCHEMBL8526909 | 0.60 | — | — | |
| SCHEMBL13576316 | 0.58 | ALDH1A1 (0.52) | ALDH1A1LMNASRD5A2MAPTHPGD | |
| SCHEMBL822185 | 0.58 | ALDH1A1 (1.00) | ALDH1A1LMNASRD5A2MAPTHPGD | |
| SCHEMBL52200 | 0.58 | ALDH1A1 (1.00) | ALDH1A1LMNASRD5A2MAPTHPGD | |
| SCHEMBL29171476 | 0.57 | CES2 (0.52) | ALDH1A1LMNAMAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026991-B1 | AROMATIC POLYESTER AND FILAMENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-21 | — | — | EP | claimed |
| EP-0026991-A1 | Aromatic polyester and filaments | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-04-15 | — | — | EP | claimed |
| EP-0026991-B1 | AROMATIC POLYESTER AND FILAMENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |