Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039640 | 0.93 | KDM4E (0.62) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10988212 | 0.80 | ALDH1A1 (0.60) | KDM4EALDH1A1TDP1BCHE | |
| SCHEMBL5239038 | 0.74 | TSHR (0.49) | KDM4EKMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL11727531 | 0.73 | KCNA3 (0.48) | KDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL28859173 | 0.73 | KCNA3 (0.48) | KDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11027702 | 0.72 | HRH1 (0.43) | KDM4EKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL10437664 | 0.72 | KCNA3 (0.46) | KDM4EKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL11669462 | 0.72 | HTR1B (0.58) | KDM4ESMN1; SMN2ALDH1A1CACNA1B | |
| SCHEMBL11726694 | 0.71 | KCNA3 (0.47) | ALDH1A1TDP1L3MBTL1POLB | |
| SCHEMBL11729477 | 0.71 | HTR1B (0.56) | KDM4ESMN1; SMN2ALDH1A1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562211-A | ANTIDEPRESSANTS | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-31 | — | — | US | disclosed |