Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046744 | 0.93 | KDM4E (0.55) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7055960 | 0.77 | DRD1 (0.68) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5239038 | 0.75 | TSHR (0.49) | KDM4EKMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL11027702 | 0.73 | HRH1 (0.43) | KDM4EKMT2AALDH1A1L3MBTL1LTA4H | |
| SCHEMBL7055956 | 0.73 | KDM4E (0.67) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6244532 | 0.73 | MMP2 (0.46) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10988212 | 0.72 | ALDH1A1 (0.60) | KDM4EALDH1A1TDP1BCHELTA4H | |
| SCHEMBL11498049 | 0.71 | TSPO (0.45) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11727531 | 0.70 | KCNA3 (0.48) | KDM4EALDH1A1TDP1L3MBTL1LTA4H | |
| SCHEMBL28859173 | 0.70 | KCNA3 (0.48) | KDM4EALDH1A1TDP1L3MBTL1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562211-A | ANTIDEPRESSANTS | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-31 | — | — | US | disclosed |