Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110467 | 1.00 | NOD1 (0.37) | NOD1ANPEPENPEPHCAR2SLC1A2 | |
| SCHEMBL110469 | 1.00 | NOD1 (0.37) | NOD1ANPEPENPEPHCAR2SLC1A2 | |
| SCHEMBL112159 | 0.89 | ALDH1A1 (0.45) | NOD1HCAR2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL112158 | 0.89 | ALDH1A1 (0.45) | NOD1HCAR2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL112160 | 0.89 | ALDH1A1 (0.45) | NOD1HCAR2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL3260928 | 0.87 | NOD1 (0.49) | NOD1HCAR2SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL3260930 | 0.87 | NOD1 (0.49) | NOD1HCAR2SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL111261 | 0.85 | NOD1 (0.51) | NOD1HCAR2ALDH1A1GRIK1GRIK2 | |
| SCHEMBL110952 | 0.85 | NOD1 (0.51) | NOD1HCAR2ALDH1A1GRIK1GRIK2 | |
| SCHEMBL109771 | 0.85 | NOD1 (0.51) | NOD1HCAR2ALDH1A1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102802605-A | Stable lipid formulations of apoptosis promoters | ABBOTT LAB | 2012-11-28 | — | — | CN | claimed |
| EP-2424499-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | Abbott Laboratories (US) | 2012-03-07 | — | — | EP | claimed |
| US-20100278905-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | ABBVIE INC. | 2010-11-04 | — | — | US | claimed |
| WO-2010127193-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | ABBOTT LABORATORIES (US) | 2010-11-04 | — | — | WO | claimed |
| EP-1379214-A1 | HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING SAME | L'OREAL, S.A. (FR) | 2004-01-14 | — | — | EP | claimed |
| US-20020159962-A1 | Hair relaxer compositions comprising at least one hydroxide compound and at least one activating agent, and methods of using the same | L'OREAL S.A. (FR) | 2002-10-31 | — | — | US | claimed |
| WO-2002067875-A1 | HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING THE SAME | L'OREAL S.A. (FR) | 2002-09-06 | — | — | WO | claimed |
| CN-105820138-A | ABT-263 crystalline forms and solvates for use in treating BCL-2 protein related diseases | ABBVIE 公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-102655858-B | ABT-263 capsule | ABBVIE (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-102802605-B | Stable lipid formulations of apoptosis promoters | ABBVIE (US) | 2015-08-12 | — | — | CN | disclosed |
| US-8927009-B2 | ABT-263 capsule | ABBVIE INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-8728516-B2 | Stabilized lipid formulation of apoptosis promoter | ABBVIE INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-8513243-B2 | ABT-263 crystalline forms | ABBVIE INC. (US) | 2013-08-20 | — | — | US | disclosed |
| US-20100278905-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | ABBVIE INC. | 2010-11-04 | — | — | US | disclosed |
| WO-2010127193-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | ABBOTT LABORATORIES (US) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010108210-A1 | RADIOLABELED FLUORINE DERIVATIVES OF METHIONINE | CRC FOR BIOMEDICAL IMAGING DEVELOPMENT LTD (AU) | 2010-09-30 | — | — | WO | disclosed |
| US-7118736-B2 | Hair relaxer compositions comprising at least one hydroxide compound and at least one activating agent, and methods of using the same | L'OREAL (FR) | 2006-10-10 | — | — | US | disclosed |
| EP-1379214-A1 | HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING SAME | L'OREAL, S.A. (FR) | 2004-01-14 | — | — | EP | disclosed |
| US-20020159962-A1 | Hair relaxer compositions comprising at least one hydroxide compound and at least one activating agent, and methods of using the same | L'OREAL S.A. (FR) | 2002-10-31 | — | — | US | disclosed |
| WO-2002067875-A1 | HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING THE SAME | L'OREAL S.A. (FR) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278905-A1 | STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER | BCL2, BAX, BCOR | NOD1 2795/4885ANPEP 4689/4885ENPEP 4640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.