Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28227421 | 0.81 | TP53 (0.44) | LMNACYP3A4CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9447753 | 0.79 | TP53 (0.47) | LMNACYP3A4CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL28247019 | 0.79 | LMNA (0.43) | LMNACYP3A4CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL5006016 | 0.77 | LMNA (0.44) | LMNACYP3A4CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL29159429 | 0.77 | LMNA (0.44) | LMNAMEN1KMT2ATP53HTT | |
| SCHEMBL964885 | 0.74 | CYP2C19 (0.50) | LMNACYP3A4CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11449628 | 0.74 | LMNA (0.42) | LMNATP53HTTTDP1ALDH1A1 | |
| SCHEMBL11849026 | 0.73 | LMNA (0.41) | LMNACYP3A4CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8330368 | 0.73 | ACP3 (0.38) | LMNACYP3A4CYP1A2CYP2C19MEN1 | |
| SCHEMBL23619853 | 0.73 | LMNA (0.45) | LMNAMEN1KMT2ATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117578-A2 | Azole-substituted alcohol derivatives | SHIONOGI & CO., LTD. (JP) | 1984-09-05 | — | — | EP | disclosed |