Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799790 | 0.86 | TDP1 (0.37) | LMNATP53HTTTDP1MEN1 | |
| SCHEMBL28227421 | 0.84 | TP53 (0.44) | LMNATP53HTTTDP1ADRA2C | |
| SCHEMBL27654341 | 0.83 | MAOA (0.35) | CYP19A1MEN1KMT2A | |
| SCHEMBL27600247 | 0.83 | MDM2 (0.37) | LMNAHTTMEN1KMT2ACYP1A2 | |
| SCHEMBL9447753 | 0.82 | TP53 (0.47) | LMNATP53HTTTDP1ADRA2C | |
| SCHEMBL28758196 | 0.81 | PSEN1 (0.33) | TDP1KCNH2 | |
| SCHEMBL29159429 | 0.79 | LMNA (0.44) | LMNATP53HTTTDP1ADRA2C | |
| SCHEMBL11047115 | 0.79 | LMNA (0.41) | LMNATP53HTTTDP1ADRA2C | |
| SCHEMBL27601029 | 0.79 | ERN1 (0.44) | LMNATP53HTTTDP1IDO1 | |
| SCHEMBL27624261 | 0.79 | CYP3A4 (0.36) | LMNATP53TDP1IDO1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929207-A | A kind of synthetic method of penta ring azoles intermediate | 齐鲁师范学院 | 2018-12-04 | — | — | CN | claimed |
| CN-108929207-A | A kind of synthetic method of penta ring azoles intermediate | 齐鲁师范学院 | 2018-12-04 | — | — | CN | disclosed |
| CN-108675994-A | A kind of method that bromo ketal reacts penta ring azoles fungicide of synthesis with 1H-1,2,4- triazoles | 齐鲁师范学院 | 2018-10-19 | — | — | CN | disclosed |
| CN-108675995-A | One kind being combined to penta ring azoles method with 4- amino -4H-1,2,4- triazolidinyls | 齐鲁师范学院 | 2018-10-19 | — | — | CN | disclosed |