SCHEMBL11047128

SCHEMBL11047128

COC(=O)CN(C(=O)[C@@H](N)CC(N)=O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
MLYCD O95822 2/20 0.43
KCNA5 P22460 1/20 0.38
NR1I2 O75469 1/20 0.38
GLA P06280 1/20 0.37
TSHR P16473 1/20 0.37
LTA4H P09960 1/20 0.37
SLC7A5 Q01650 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPK1 P28482 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1822076 0.90 MLYCD (0.44) ALDH1A1MLYCDKCNA5GLATSHR
Hydrochloric Acid SCHEMBL11694104 0.89 MLYCD (0.43) ALDH1A1MLYCDKCNA5GLATSHR
Phosphoric Acid SCHEMBL11509542 0.86 MLYCD (0.41) ALDH1A1MLYCDKCNA5GLATSHR
Hydrochloric Acid SCHEMBL5967432 0.85 MLYCD (0.44) ALDH1A1MLYCDKCNA5GLATSHR
Trifluoroacetic Acid SCHEMBL8626777 0.85 MLYCD (0.48) MLYCDKCNA5NR1I2
SCHEMBL10511658 0.84 ACE (0.40) ALDH1A1MLYCDGLATSHR
SCHEMBL5967205 0.83 MLYCD (0.50) ALDH1A1MLYCDKCNA5NR1I2GLA
Hydrochloric Acid SCHEMBL5967352 0.83 MLYCD (0.43) ALDH1A1MLYCDGLATSHRLTA4H
Hydrochloric Acid SCHEMBL5967108 0.83 MLYCD (0.45) ALDH1A1MLYCDKCNA5GLATSHR
Hydrochloric Acid SCHEMBL5967360 0.83 SLC7A5 (0.47) MLYCDSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4439524-A Stereoselective resolution of phenylglycine derivatives with enzyme resins BAYER AKTIENGESELLSCHAFT (DE) 1984-03-27 US disclosed
US-3972860-A L-aspartyl-L-phenylglycine esters of lower alkanols MORIARTY CAROLE L 1976-08-03 US disclosed