SCHEMBL1822076

SCHEMBL1822076

COC(=O)CN(C(=O)[C@@H](N)CC(=O)O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 2/20 0.44
KCNA5 P22460 1/20 0.39
ALDH1A1 P00352 3/20 0.38
GLA P06280 1/20 0.38
TSHR P16473 1/20 0.38
LTA4H P09960 3/20 0.38
SLC7A5 Q01650 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPK1 P28482 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11694104 0.99 MLYCD (0.43) MLYCDKCNA5ALDH1A1GLATSHR
Phosphoric Acid SCHEMBL11509542 0.95 MLYCD (0.41) MLYCDKCNA5ALDH1A1GLATSHR
SCHEMBL11047128 0.90 ALDH1A1 (0.44) MLYCDKCNA5ALDH1A1GLATSHR
Hydrochloric Acid SCHEMBL5967432 0.86 MLYCD (0.44) MLYCDKCNA5ALDH1A1GLATSHR
Trifluoroacetic Acid SCHEMBL8626777 0.86 MLYCD (0.48) MLYCDKCNA5
SCHEMBL6930491 0.85 SMN1; SMN2 (0.39) MLYCDALDH1A1GLATSHRSLC7A5
SCHEMBL27459998 0.85 ACE (0.41) MLYCDALDH1A1GLATSHR
SCHEMBL1562840 0.85 ACE (0.41) MLYCDALDH1A1GLATSHR
SCHEMBL5967205 0.84 MLYCD (0.50) MLYCDKCNA5ALDH1A1GLATSHR
Hydrochloric Acid SCHEMBL10509889 0.84 ACE (0.40) MLYCDALDH1A1GLATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2723186-A1 POLYDIORGANOSILOXANE-ENCAPSULATED ACTIVE INGREDIENT, METHOD FOR THE PREPARATION THEREOF, AND CHEWING GUM COMPRISING SAME Intercontinental Great Brands LLC (US) 2014-04-30 EP claimed
WO-2013003409-A1 POLYDIORGANOSILOXANE-ENCAPSULATED ACTIVE INGREDIENT, METHOD FOR THE PREPARATION THEREOF, AND CHEWING GUM COMPRISING SAME KRAFT FOODS GLOBAL BRANDS LLC (US) 2013-01-03 WO claimed
US-20110104329-A1 TASTE POTENTIATOR COMPOSITIONS AND EDIBLE CONFECTIONERY AND CHEWING GUM PRODUCTS CONTAINING SAME KRAFT FOODS GLOBAL BRANDS LLC 2011-05-05 US claimed
US-7851005-B2 Taste potentiator compositions and beverages containing same CADBURY ADAMS USA LLC (US) 2010-12-14 US claimed
EP-2701532-B1 ENCAPSULATED ACID, METHOD FOR THE PREPARATION THEREOF, AND CHEWING GUM COMPRISING SAME INTERCONTINENTAL GREAT BRANDS LLC (US) 2017-11-15 EP disclosed
US-20170245522-A1 ENCAPSULATED ACID, METHOD FOR THE PREPARATION THEREOF, AND CHEWING GUM COMPRISING SAME INTERCONTINENTAL GREAT BRANDS LLC (US) 2017-08-31 US disclosed
US-9737082-B2 Chewing gum composition comprising encapsulated acid INTERCONTINENTAL GREAT BRANDS LLC (US) 2017-08-22 US disclosed
WO-2017105634-A1 CHEWING GUM COMPOSITIONS HAVING CONTROLLED RELEASE OF COOLING AGENTS AND METHODS OF MANUFACTURE INTERCONTINENTAL GREAT BRANDS LLC (US) 2017-06-22 WO disclosed
US-9504266-B2 Photodegradable gum base, a chewing gum comprising the photodegradable gum base and methods of making the same INTERCONTINENTAL GREAT BRANDS LLC (US) 2016-11-29 US disclosed
EP-3043653-A1 CHEWING GUM COMPOSITION COMPRISING A MICRO-ENCAPSULATED FLAVOUR IN A MATRIX COMPRISING PROTEIN Intercontinental Great Brands LLC (US) 2016-07-20 EP disclosed
US-20160192674-A1 CHEWING GUM COMPOSITION COMPRISING A MICRO-ENCAPSULATED FLAVOUR IN A MATRIX COMPRISING PROTEIN INTERCONTINENTAL GREAT BRANDS LLC (US) 2016-07-07 US disclosed
US-20160095331-A1 COLORED WAX COMPOSITIONS INTERCONTINENTAL GREAT BRANDS LLC (US) 2016-04-07 US disclosed
EP-0048051-B1 DIPEPTIDE SWEETENER STAMICARBON B.V. (NL) 1984-12-12 EP disclosed
US-4371464-A Dipeptide sweetener STAMICARBON, B.V. (NL) 1983-02-01 US disclosed
EP-0048051-A1 Dipeptide sweetener STAMICARBON B.V. (NL) 1982-03-24 EP disclosed
US-4260684-A Stereoselective resolution of phenylglycine derivatives and 4-hydroxyphenylglycine derivatives with enzyme resins BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
US-4260684-A Stereoselective resolution of phenylglycine derivatives and 4-hydroxyphenylglycine derivatives with enzyme resins BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
US-3978034-A L-Aspartyl dipeptides as sweetening agents E. R. SQUIBB & SONS, INC. (US) 1976-08-31 US disclosed
US-3972860-A L-aspartyl-L-phenylglycine esters of lower alkanols MORIARTY CAROLE L 1976-08-03 US disclosed
US-3972860-A L-aspartyl-L-phenylglycine esters of lower alkanols MORIARTY CAROLE L 1976-08-03 US disclosed