Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106453 | 0.82 | ALDH1A1 (0.65) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11043915 | 0.82 | SMN1; SMN2 (0.47) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11103911 | 0.80 | ALDH1A1 (0.58) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11047797 | 0.80 | HSD17B10 (0.45) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11045059 | 0.76 | SMN1; SMN2 (0.54) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11109630 | 0.76 | HSD17B10 (0.77) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11103946 | 0.75 | KDM4E (0.76) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11102397 | 0.74 | KDM4E (0.64) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11041195 | 0.74 | TSHR (0.44) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11046894 | 0.74 | HSD17B10 (0.51) | HSD17B10KDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451448-A | 1-Substituted tricyclic quinazolinones useful as tranquilizers | SANDOZ, INC. (US) | 1984-05-29 | — | — | US | disclosed |