Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CLPP | Q16740 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046894 | 0.94 | HSD17B10 (0.51) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11106453 | 0.81 | ALDH1A1 (0.65) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11043915 | 0.81 | SMN1; SMN2 (0.47) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11047162 | 0.80 | HSD17B10 (0.46) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11041195 | 0.79 | TSHR (0.44) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11042701 | 0.78 | CYP2D6 (0.40) | HSD17B10HTR3AHRH4CYP2D6GHSR | |
| SCHEMBL11103911 | 0.78 | ALDH1A1 (0.58) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11044568 | 0.77 | ADORA2A (0.44) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11043885 | 0.77 | ADORA2A (0.44) | HSD17B10KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11044466 | 0.75 | KCNH2 (0.44) | HSD17B10KDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451448-A | 1-Substituted tricyclic quinazolinones useful as tranquilizers | SANDOZ, INC. (US) | 1984-05-29 | — | — | US | disclosed |