Butyl Fumarate

Butyl Fumarate

SCHEMBL4376900

CCCCOC(=O)/C=C\C(=O)O.[SnH4]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 1.00
ATM Q13315 1/20 0.83
MAPT P10636 1/20 0.61
RAB9A P51151 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
HPGD P15428 1/20 0.59
TSHR P16473 1/20 0.59
ALDH1A1 P00352 1/20 0.50
APP P05067 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyl Fumarate SCHEMBL43165 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Maleic Acid SCHEMBL28199237 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL43164 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL124163 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Maleic Acid SCHEMBL27358295 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL27358297 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL29604195 1.00 HCAR2 (1.00) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL6905849 0.98 HCAR2 (0.96) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL1223794 0.98 HCAR2 (0.96) HCAR2ATMMAPTRAB9ANPSR1
Butyl Fumarate SCHEMBL18628256 0.98 HCAR2 (0.96) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119463159-A Silanized polyphenyl ether resin and preparation method thereof, high-temperature-resistant low-dielectric material and preparation method thereof 北京化工大学 2025-02-18 CN claimed
CN-119410019-A Hard chlorinated polyvinyl chloride foaming material and preparation method thereof 山东高信化学股份有限公司 2025-02-11 CN claimed
CN-118675804-A Smooth copper sheath fireproof cable with excellent moisture resistance and preparation method 浙江万马股份有限公司 2024-09-20 CN claimed
CN-115135632-B Preparation method of ester compound 韩华思路信(株) 2024-03-29 CN claimed
US-20230078583-A1 PREPARATION METHOD OF ESTER COMPOUND HANWHA SOLUTIONS CORPORAION (KR) 2023-03-16 US claimed
EP-4105195-A1 ESTER-BASED COMPOUND PRODUCTION METHOD Hanwha Solutions Corporation (KR) 2022-12-21 EP claimed
CN-114773747-A Application of dihydropyridine polymer in preparation of PVC (polyvinyl chloride) material 兰州金睿合新材料科技有限责任公司 2022-07-22 CN claimed
CN-113292799-A Transparent PVC-U electrical casing and preparation method thereof 武汉市九牧管业科技有限公司 2021-08-24 CN claimed
WO-2021162284-A1 ESTER-BASED COMPOUND PRODUCTION METHOD 한화솔루션 주식회사 2021-08-19 WO claimed
EP-3688082-A1 COMPOSITIONS COMPRISING A TIN-BASED CATALYST AND TITANIUM DIOXIDE FOR MOISTURE CURE OF SILANE-FUNCTIONALIZED ETHYLENIC POLYMERS Dow Global Technologies LLC (US) 2020-08-05 EP claimed
CN-110832008-A Method for producing fatty acid monoesters of polyoxyethylene, esters produced thereby and use thereof 沙特基础工业全球技术有限公司 2020-02-21 CN claimed
WO-2019067440-A1 COMPOSITIONS COMPRISING A TIN-BASED CATALYST AND TITANIUM DIOXIDE FOR MOISTURE CURE OF SILANE-FUNCTIONALIZED ETHYLENIC POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-04 WO claimed
CN-1506545-A Flooring and wall covering based on concrete with antimicrobe purpose 塞美克斯品牌环球有限公司 2004-06-23 CN claimed
US-20260138943-A1 METHOD FOR PREPARING ESTER-BASED COMPOSITION HANWHA SOLUTIONS CORP (KR) 2026-05-21 US disclosed
US-12522557-B2 Method of preparing diester-based material LG CHEM, LTD. (KR) 2026-01-13 US disclosed
EP-4023628-B1 METHOD FOR PREPARING DIESTER-BASED MATERIAL LG CHEMICAL LTD (KR) 2025-12-24 EP disclosed
EP-0012990-A1 Talc containing moulding compositions on the basis of vinyl chloride polymers KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1980-07-09 EP disclosed
US-4125533-A STABILIZERS SANKYO CO. LTD. (JP) 1978-11-14 US disclosed
US-4016168-A STABILIZERS FOR POLYMERS SANKYO COMPANY LIMITED (JA) 1977-04-05 US disclosed
US-3984371-A PIPERIDINE DERIVATIVES SANKYO COMPANY LIMITED (JA) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138943-A1 METHOD FOR PREPARING ESTER-BASED COMPOSITION NCEH1, ADH1A, TECR HCAR2 1937/4885ATM 2026/4885MAPT 2643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.