Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.61 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24833975 | 0.98 | CYP2B6 (0.64) | CYP2B6TBXAS1HRH4HRH3CYP19A1 | |
| SCHEMBL11049587 | 0.98 | CYP2B6 (0.64) | CYP2B6TBXAS1HRH4HRH3CYP19A1 | |
| SCHEMBL16163635 | 0.93 | CYP2B6 (0.62) | CYP2B6TBXAS1HRH4HRH3CYP19A1 | |
| SCHEMBL11051486 | 0.87 | CYP2B6 (0.68) | CYP2B6TBXAS1HRH4HRH3CYP19A1 | |
| SCHEMBL11050188 | 0.87 | CYP2B6 (0.68) | CYP2B6TBXAS1HRH4HRH3CYP19A1 | |
| Iodide SCHEMBL16164357 | 0.86 | CYP2B6 (0.66) | CYP2B6TBXAS1HRH4HRH3CYP19A1 | |
| SCHEMBL24833961 | 0.85 | CYP2B6 (0.53) | CYP2B6TBXAS1HRH4HRH3CYP19A1 | |
| SCHEMBL10784468 | 0.85 | TBXAS1 (0.49) | CYP2B6TBXAS1HRH4HRH3GAA | |
| SCHEMBL6174188 | 0.85 | TBXAS1 (0.52) | CYP2B6TBXAS1HRH4HRH3CYP19A1 | |
| SCHEMBL11720830 | 0.82 | TBXAS1 (0.53) | CYP2B6TBXAS1HRH4HRH3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000951-B1 | PHARMACEUTICAL FORMULATIONS COMPRISING 1-SUBSTITUTED IMIDAZOLES, 1-SUBSTITUTED IMIDAZOLES AND 1-SUBSTITUTED IMIDAZOLES FOR USE IN THE TREATMENT OR PROPHYLAXIS OF THROMBO-EMBOLIC DISORDERS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-23 | — | — | EP | disclosed |
| EP-0000950-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF AND THEIR SYNTHESIS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-02-01 | — | — | EP | disclosed |
| US-4317830-A | ANTISHOCK AGENTS, ANTICOAGULANTS | BURROUGHS WELLCOME CO. (US) | 1982-03-02 | — | — | US | disclosed |
| US-4284641-A | ANTITHROMBOEMBOLIC AGENT | BURROUGHS WELLCOME CO. (US) | 1981-08-18 | — | — | US | disclosed |
| EP-0000950-A1 | Imidazole derivatives and salts thereof and their synthesis | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-03-07 | — | — | EP | disclosed |
| EP-0000951-A1 | Pharmaceutical Formulations comprising 1-substituted imidazoles, 1-substituted imidazoles and 1-substituted imidazoles for use in the treatment or prophylaxis of thrombo-embolic disorders | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-03-07 | — | — | EP | disclosed |