Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047273 | 0.86 | HPGD (0.38) | HPGDKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL11053903 | 0.84 | HPGD (0.37) | HPGDKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL24787159 | 0.81 | KDM4E (0.34) | HPGDKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL12566682 | 0.77 | ALDH1A1 (0.45) | HPGDKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL809214 | 0.77 | TRPV4 (0.39) | HPGDALDH1A1 | |
| SCHEMBL30542039 | 0.77 | TRPV4 (0.39) | HPGDALDH1A1 | |
| SCHEMBL18162323 | 0.76 | KDM4E (0.47) | HPGDKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL28435815 | 0.74 | TRPV4 (0.38) | HPGDALDH1A1 | |
| SCHEMBL16581505 | 0.74 | TRPV4 (0.38) | HPGDALDH1A1 | |
| SCHEMBL16306934 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119701-A1 | Grignard syntheses | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-09-26 | — | — | EP | disclosed |