Diphenylmethane

Diphenylmethane

SCHEMBL11047435

C1=C(CCC2=CCCCC2)CCCC1.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
HPGD P15428 4/20 0.55
EPHX1 P07099 1/20 0.54
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
NPSR1 Q6W5P4 2/20 0.49
USP2 O75604 1/20 0.49
MAPT P10636 3/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALOX12 P18054 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
CALM1 P0DP23 1/20 0.46
LMNA P02545 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HTR1A P08908 1/20 0.43
HTR7 P34969 1/20 0.43
HTR6 P50406 1/20 0.43
ALOX15 P16050 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5798174 0.90 HPGD (0.59) ALDH1A1HPGDEPHX1MEN1KMT2A
SCHEMBL1399903 0.88 ALDH1A1 (0.50) ALDH1A1HPGDEPHX1MEN1KMT2A
SCHEMBL6806443 0.86 ALDH1A1 (0.49) ALDH1A1HPGDEPHX1MEN1KMT2A
SCHEMBL112394 0.86 ALDH1A1 (0.49) ALDH1A1HPGDEPHX1MEN1KMT2A
SCHEMBL111084 0.86 ALDH1A1 (0.49) ALDH1A1HPGDEPHX1MEN1KMT2A
SCHEMBL8206338 0.86 ALDH1A1 (0.49) ALDH1A1HPGDEPHX1MEN1KMT2A
SCHEMBL28561920 0.85 ALDH1A1 (0.48) ALDH1A1HPGDEPHX1MEN1KMT2A
Hydrochloric Acid SCHEMBL3407515 0.85 ALDH1A1 (0.48) ALDH1A1HPGDEPHX1MEN1KMT2A
SCHEMBL2333440 0.82 CALM1 (0.46) ALDH1A1HPGDEPHX1MEN1KMT2A
SCHEMBL23022991 0.79 HPGD (0.63) ALDH1A1HPGDEPHX1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4533752-A CONVERSION TO CYCLIC OLEFINS PURDUE RESEARCH FOUNDATION (US) 1985-08-06 US disclosed