Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.38 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 7/20 | 0.38 |
| ▸ | AR | P10275 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042166 | 0.84 | PGR (0.40) | SHBGSERPINA6ALDH1A1PGRAR | |
| SCHEMBL11048229 | 0.84 | PGR (0.40) | SHBGSERPINA6ALDH1A1PGRAR | |
| SCHEMBL1421923 | 0.81 | CYP19A1 (0.51) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL2318050 | 0.81 | CYP19A1 (0.51) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL9327894 | 0.81 | CYP19A1 (0.51) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL16661465 | 0.81 | CYP19A1 (0.51) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL11044681 | 0.81 | CYP19A1 (0.48) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL11140879 | 0.77 | PGR (0.52) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL11044038 | 0.77 | PGR (0.40) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL23397900 | 0.74 | CYP19A1 (0.48) | SHBGSERPINA6SLC22A1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464365-A | 11β-Chloro-Δ15 -steroids, a process for their preparation and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-07 | — | — | US | disclosed |