Styrene

Styrene

SCHEMBL11047606

C1CCCCC1.C=C(C)c1ccccc1.C=CC=C.C=Cc1ccccc1

nearest known ligand 0.57

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
AKT1 P31749 1/20 0.34
MEN1 O00255 1/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
AKR1C3 P42330 1/20 0.32
GLA P06280 1/20 0.32
HDAC2 Q92769 1/20 0.32
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL2941460 0.94 ALDH1A1 (0.56) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL315930 0.91 ALDH1A1 (0.61) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL2779087 0.89 ALDH1A1 (0.50) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL27519908 0.85 ALDH1A1 (0.54) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL10988914 0.85 ALDH1A1 (0.45) ALDH1A1TSHRTDP1TP53CYP3A4
Butadiene SCHEMBL9246918 0.84 AKT1 (0.44) ALDH1A1TSHRTDP1AKT1MEN1
Benzene SCHEMBL11589819 0.84 AKT1 (0.44) ALDH1A1TSHRTDP1AKT1MEN1
Butadiene SCHEMBL2781676 0.84 AKT1 (0.44) ALDH1A1TSHRTDP1AKT1MEN1
Styrene SCHEMBL6674902 0.82 ALDH1A1 (0.67) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL2137486 0.82 ALDH1A1 (0.67) ALDH1A1TSHRTDP1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4431777-A Block copolymers of diene having their terminal end blocks of a random copolymer of styrene or alkylstyrene and an alpha-methylstyrene THE DOW CHEMICAL COMPANY (US) 1984-02-14 US disclosed