Styrene

Styrene

SCHEMBL2941460

C=C(C)c1ccccc1.C=CC=C.C=Cc1ccccc1

nearest known ligand 0.64

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TSHR P16473 2/20 0.56
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.40
AKT1 P31749 1/20 0.38
AKR1C3 P42330 1/20 0.35
GLA P06280 1/20 0.35
HDAC8 Q9BY41 2/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
MAPT P10636 2/20 0.34
AKR1C1 Q04828 1/20 0.34
PLIN1 O60240 1/20 0.34
LMNA P02545 1/20 0.34
BCHE P06276 1/20 0.34
TNFRSF1A P19438 1/20 0.34
ACHE P22303 1/20 0.34
MAOB P27338 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL315930 0.96 ALDH1A1 (0.61) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL11047606 0.94 ALDH1A1 (0.50) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL2779087 0.94 ALDH1A1 (0.50) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL27519908 0.90 ALDH1A1 (0.54) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL10988914 0.90 ALDH1A1 (0.45) ALDH1A1TSHRTDP1TP53CYP3A4
Butadiene SCHEMBL9246918 0.89 AKT1 (0.44) ALDH1A1TSHRTDP1AKT1CES2
Butadiene SCHEMBL2781676 0.89 AKT1 (0.44) ALDH1A1TSHRTDP1AKT1CES2
Benzene SCHEMBL11589819 0.89 AKT1 (0.44) ALDH1A1TSHRTDP1AKT1CES2
Styrene SCHEMBL6674902 0.87 ALDH1A1 (0.67) ALDH1A1TSHRTDP1TP53CYP3A4
Styrene SCHEMBL2137486 0.87 ALDH1A1 (0.67) ALDH1A1TSHRTDP1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2143353-B1 OUTER SOLES AND SHOES ASICS CORP (JP) 2015-09-02 EP disclosed
US-20100154253-A1 OUTER SOLE AND SHOES ASICS CORPORATION (JP) 2010-06-24 US disclosed
EP-2143353-A1 OUTER SOLES AND SHOES ASICS Corporation (JP) 2010-01-13 EP disclosed
US-20030065099-A1 Block copolymers containing hydrogenated vinyl aromatic/(alpha-alkylstyrene) copolymer blocks HAHN STEPHEN F (US) 2003-04-03 US disclosed
WO-2003025026-A1 BLOCK COPOLYMERS CONTAINING HYDROGENATED VINYL AROMATIC/(ALPHA-ALKYLSTYRENE)COPOLYMER BLOCKS DOW GLOBAL TECHNOLOGIES INC. (US) 2003-03-27 WO disclosed
CN-1276812-A Compositions of interpolymers of alpha-olefin monomers with one or more vinyl or vinylidene aromatic monomers DOW CHEMICAL CO (US) 2000-12-13 CN disclosed
US-4431777-A Block copolymers of diene having their terminal end blocks of a random copolymer of styrene or alkylstyrene and an alpha-methylstyrene THE DOW CHEMICAL COMPANY (US) 1984-02-14 US disclosed